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Mouse Anti-Chicken CD45-APC

  • Catalog number
    MBS673900
  • Product name
    Mouse Anti-Chicken CD45-APC
  • Size
    5x0.1 mg
  • Products type
    Antibody
  • Products short name
    [CD45]
  • Products name syn
    [Mouse Anti-Chicken CD45 - Allophycocyanin; Mouse Anti-Chicken CD45]
  • Other names
    [CD45; Receptor-type tyrosine-protein phosphatase C; receptor-type tyrosine-protein phosphatase C; CD45 antigen; T200 glycoprotein; OTTHUMP00000033813; OTTHUMP00000033816; OTTHUMP00000033817; OTTHUMP00000038574; leukocyte common antigen; leukocyte-common antigen; T200 leukocyte common antigen; protein tyrosine phosphatase, receptor type, c polypeptide; protein tyrosine phosphatase, receptor type, C; Leukocyte common antigen; L-CA; T200]
  • Other gene names
    [PTPRC; PTPRC; LCA; LY5; B220; CD45; L-CA; T200; CD45R; GP180; CD45]
  • Clonality
    Monoclonal
  • Isotype
    Mouse IgM kappa
  • Clone
    [LT40]
  • Host
    Mouse
  • Reactivity
    Chicken
  • Specificity
    Chicken CD45 (Mr 190 to 215-kDa). Chicken CD45 is a transmembrane glycoprotein expressed on all leukocytes. B lineage cells in the bursa of Fabricius express the 215 kDa isoform while T lineage cells bear the 190 kDa variant. These high molecular weight molecules have intrinsic phosphotyrosine phosphatase activity characteristic of mammalian CD45.1 Levels of CD45 expression detected by MAb LT40 in the avian thymus are heterogeneous with approximately 90% of thymocytes expressing fourfold higher levels of surface CD45 (CD45hi) than do the remaining 10% (CD45lo) of thymocytes. The CD45lo population contains exclusively thymocytes with the CD3-CD4-CD8lo phenotype characteristic of the immediate precursors to the CD3- CD4+CD8+ thymic population which are CD45hi. This shift from low to high levels of surface CD45 expression is concomitant with the transition from CD4-CD8lo to CD4+CD8+ and before the expression of CD3. The ability of MAb LT40 to discriminate this CD45lo subpopulation provides a suitable marker for the CD3-CD4-CD8lo immediate precursors to the CD3-CD4+CD8+ thymocytes.1
  • Form
    Allophycocyanin (APC) Conjugate
  • Storage stability
    The purified (UNLB) antibody is supplied as 0.5 mg of purified immunoglobulin in 1.0 mL of 100 mM borate buffered saline, pH 8.2. No preservatives or amine-containing buffer salts added. Store at 2- 8 degree C. The fluorescein (FITC) conjugate is supplied as 0.5 mg in 1.0 mL of PBS/NaN3. Store at 2-8 degree C. The biotin (BIOT) conjugate is supplied as 0.5 mg in 1.0 mL of PBS/NaN3. Store at 2-8 degree C. The R-phycoerythrin (R-PE) and allophycocyanin (APC) conjugates are supplied as 0.1 mg in 1.0 mL of PBS/NaN3 and a stabilizing agent. Store at 2-8 degree C. Do not freeze! The Spectral Red (SPRD) conjugate is supplied as 0.1 mg in 1.0 mL of PBS/NaN3 and a stabilizing agent. Store at 2-8 degree C. Do not freeze! Protect conjugated forms from light. Each reagent is stable for the period shown on the bottle label if stored as directed.
  • Tested application
    Flow Cytometry; Immunoprecipitation
  • Alternative to gene target
    • [ "adenomatous polyposis coli", "BTPS2 and DP2 and DP2.5 and DP3 and GS and PPP1R46", "APC and IDBG-37007 and ENSG00000134982 and 324", "microtubule plus-end binding", "nuclei", "Apc and IDBG-134573 and ENSMUSG00000005871 and 11789", "BT.25770 and IDBG-644937 and ENSBTAG00000018852 and 533233" ]
  • Gene target
    - CD45-APC
    • Gene info
    Gene info
    Locus Specific Databases:Adenomatous polyposis coli mutation databaseUMD Locus Specific DatabasesGlobal Variome shared LOVDAPC database at LOVD-ChinaLOVD - Leiden Open Variation DatabaseLRG_130
    Gene info
    • Identity:HGNC:9666
    • Gene:PTPRC
    • Long gene name:protein tyrosine phosphatase receptor type C
    • Synonyms:LCAT200GP180
    • Discovery year:1986-01-01
    • Entrez gene record:5788
    • Pubmed identification:2169617
    • RefSeq identity:NM_002838
    • Classification:Protein tyrosine phosphatases receptor type, Fibronectin type III domain containing, CD molecules
    • VEGA ID:OTTHUMG00000035702
    Locus Specific Databases:PTPRCbase: Mutation registry for CD45 deficiencyLRG_95
  • Gene symbol
    PTPRCAP, APC, PTPRC
  • isotype filter
    • Mouse IgM kappa
  • Short name
    Mouse Anti- CD45-APC
  • Label
    APC
  • label filter
    • APC
  • technique filter
    • anti-
    • Mouse
    • anti
  • Technique
    anti-, Mouse, anti, antibody to, antibodies, mouses
  • Alternative technique
    murine, antibodies