- Catalog numberMBS673433
- Product nameHamster Anti-Mouse CD69/VEA-PE/CY7
- Size0.1 mg
- PriceAsk For Price
- Products typeAntibody
- Products short name[CD69 (VEA)]
- Products name syn[Hamster Anti-Mouse CD69/VEA - Phycoerythrin-Labeled/CY7; Hamster Anti-Mouse CD69 (VEA)]
- Other names[CD69 antigen; Early activation antigen CD69; early activation antigen CD69; Very Early Activation Antigen; CD69 antigen]
- Other gene names[Cd69; AIM; VEA; AI452015; 5830438K24Rik]
- ClonalityMonoclonal
- IsotypeArmenian Hamster IgG lambda
- Clone[H1.2F3]
- HostArmenian Hamster
- ReactivityMouse
- SpecificityMouse CD69/Very Early Activation Antigen (VEA), Mr 85 kDa (unreduced) CD69, also known as very early activation (VEA) antigen, is a disulfide-linked transmembrane homodimer whose differentially glycosylated subunits range from 35-39 kDa.^1,2 It is a C-type lectin, most closely related to the NKR-P1 and Ly-49 NK cell-activation molecules.^3 CD69 is widely expressed on hematopoietic cells, including lymphocytes, neutrophils and eosinophils.^1-4 Although not detectable on resting lymphocytes, its expression is rapidly (within 2 hours) upregulated upon activation of T, B and NK cells, and neutrophils.4 Constitutive expression of CD69 on subsets of thymocytes suggests that it may be involved in regulation of developmental events in addition to its role in activation of a variety of hematopoietic cells.^4,5 MAb H1.2F3 augments PMA-induced T-cell proliferation,^1,6 and induces redirected lysis of Fc receptor-bearing target cells by NK cells.^7
- FormR - phycoerythrin - Cyanine 7 (R - PE - CY7) Conjugate
- Storage stabilityThe purified (UNLB) antibody is supplied as 0.5 mg of purified immunoglobulin in 1.0 mL of 100 mM borate buffered saline, pH 8.2. No preservatives or amine-containing buffer salts added. Store at 2-8 degree C. The fluorescein (FITC) conjugate is supplied as 0.5 mg in 1.0 mL of PBS/NaN3. Store at 2-8 degree C. The biotin (BIOT) conjugate is supplied as 0.5 mg in 1.0 mL of PBS/NaN3. Store at 2-8 degree C. The R-phycoerythrin (R-PE) conjugate is supplied as 0.1 mg in 1.0 mL or 0.2 mg in 2.0 mL of PBS/NaN3 and a stabilizing agent. Store at 2-8 degree C. Do not freeze! The allophycocyanin (APC) conjugate is supplied as 100 tests in 1.0 mL of PBS/NaN3 and a stabilizing agent. Store at 2-8 degree C. Do not freeze! The Spectral Red (SPRD) and R-phycoerythrin-Cyanine 7 (R-PE-CY 7) conjugates are supplied as 0.1 mg in 1.0 mL of PBS/NaN3 and a stabilizing agent. Store at 2-8 degree C. Do not freeze! The low endotoxin, azide-free (LE/AF) antibody is supplied as 0.5 mg purified immunoglobulin in 1.0 mL of PBS. Aliquot and store at or below -20 degree C. Protect conjugated forms from light. Aliquot and freeze the low endotoxin, azide-free product at -20 degree C immediately upon receipt. Each reagent is stable for the period shown on the bottle label if stored as directed.
- Tested applicationFlow Cytometry; Immunohistochemistry (Acetone Fixed/Frozen Sections); Immunoprecipitation
- Alternative to gene target
- [ "CD69 molecule", "AIM and BL-AC/P26 and CLEC2C and EA1 and GP32/28 and MLR-3", "CD69 and IDBG-18077 and ENSG00000110848 and 969", "carbohydrate binding", "Cell surfaces", "Cd69 and IDBG-191849 and ENSMUSG00000030156 and 12515", "CD69 and IDBG-639618 and ENSBTAG00000002135 and 281058" ]
- Gene targetCD69/VEA-PE/
- Identity:HGNC:1694
- Gene:CD69
- Long gene name:CD69 molecule
- Synonyms gene name:CD69 antigen (p60, early T-cell activation antigen)
- Synonyms:CLEC2C
- Discovery year:1992-08-06
- Entrez gene record:969
- Pubmed identification:1612643
- Classification:C-type lectin domain containing, CD molecules
- VEGA ID:OTTHUMG00000168481
- Identity:HGNC:3492
- Gene:ETV3
- Long gene name:ETS variant transcription factor 3
- Synonyms gene name:ets variant gene 3, ETS family transcriptional repressor, ETS variant 3
- Synonyms:PE-1,
- Discovery year:1994-12-15
- Entrez gene record:2117
- Pubmed identification:8020980
- RefSeq identity:NM_005240
- Classification:ETS transcription factor family
- VEGA ID:OTTHUMG00000034298
- Identity:HGNC:3444
- Gene:ERF
- Long gene name:ETS2 repressor factor
- Synonyms gene name:Ets2 repressor factor
- Synonyms:PE-2PE2
- Discovery year:1998-07-17
- Entrez gene record:2077
- Pubmed identification:7588608, 9192842
- RefSeq identity:NM_006494
- Classification:ETS transcription factor family
- VEGA ID:OTTHUMG00000182788
- Gene symbolCD69, ETV3, ERF
- isotype filter
- Armenian Hamster IgG lambda
- Short nameAnti-Mouse CD69/VEA-PE/
- LabelPE
- label filter
- PE
- technique filter
- anti-
- Mouse
- anti
- Techniqueanti-, Mouse, anti, antibody to, antibodies, mouses
- Alternative techniquemurine, antibodies