- Catalog numberMBS221357
- Product nameGOAT ANTI SYK
- Size5x0.1 mg
- PriceAsk For Price
- Products typeAntibody
- Products short name[SYK]
- Other names[tyrosine-protein kinase SYK isoform Syk(S); Tyrosine-protein kinase SYK; tyrosine-protein kinase SYK; spleen tyrosine kinase; Spleen tyrosine kinase; p72-Syk]
- Products gene name[SYK]
- Other gene names[SYK; SYK; p72-Syk]
- ClonalityPolyclonal
- IsotypeIgG
- HostGoat, The goat polyclonal antibodies are directed against human genes or rabbit or mouse IgGs (H +L) chain primary antibodies and conjugated for detection. It are very good secondary antibodies that are affinity purified and have a good affinity themselves too. Often KLH is coupled to the antigen so anti KLH can be present in the vial.
- ReactivityDog (Expected from Sequence), Mouse (Expected from Sequence), Rat (Expected from Sequence)
- SpecificityThis item detects an epitope within the internal region of SYK, a 70kD non-receptor protein tyrosine kinase whose role differs in haematopoietic and non haematopoietic stem cells. In haematopoietic cells SYK is involved in the proximal signalling downstream of activated immunoreceptors (BCR, TCR, Fc receptors), thereby orchestrating a complex series of cellular responses such as cell proliferation, differentiation, survival and phagocytosis. In epithelial cells SYK appears to function as a negative regulator of related events. Furthermore, SYK has been shown to promote expression or secretion of inflammation-related molecules in lung epithelial cells. SYK appears to be required for vascular integrity during development, thus, manipulation of SYK function in endothelial cells could potentially modulate tumour-associated angiogenesis. SYK also has been shown to interact with Epstein-Barr virus LMP2A.
- FormPurified Purified IgG - liquid
- ConcentrationIgG concentration 0.5mg/ml
- Storage stabilityStore at 4 degree C or at -20 degree C if preferred. Storage in frost-free freezers is not recommended. This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use. Shelf Life: 18 months from date of despatch.
- Tested applicationELISA (EIA), Western Blot (WB)
- Alternative to gene target
- [ "spleen tyrosine kinase", "p72-Syk", "SYK and IDBG-75571 and ENSG00000165025 and 6850", "transferase activity", "Plasma membranes", "Syk and IDBG-152695 and ENSMUSG00000021457 and 20963", "SYK and IDBG-637026 and ENSBTAG00000004767 and 515515" ]
- Gene targetSYK
- Identity:HGNC:11491
- Gene:SYK
- Long gene name:spleen associated tyrosine kinase
- Synonyms gene name:spleen tyrosine kinase
- Discovery year:1994-12-13
- Entrez gene record:6850
- Pubmed identification:8082894, 1423621
- Classification:Syk family tyrosine kinases, SH2 domain containing
- VEGA ID:OTTHUMG00000020200
- Gene symbolSYK
- isotype filter
- IgG
- Short nameGOAT ANTI SYK
- technique filter
- anti
- Goat
- Techniqueanti, Goat, antibody to, goats
- Alternative techniqueantibodies, caprine