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CD37 (Peripheral Mature B-Cell Marker) Mouse Monoclonal Antibody

  • Catalog number
    MBS438928
  • Product name
    CD37 (Peripheral Mature B-Cell Marker) Mouse Monoclonal Antibody
  • Size
    5x0.1 mg (Without BSA & Azide at 1mg/mL)
  • Products type
    Antibody
  • Products short name
    [CD37]
  • Products name syn
    [Cell differentiation antigen 37; GP52 40; Tetraspanin-26; Tspan-26; TSPAN26]
  • Other names
    [leukocyte antigen CD37 isoform B; Leukocyte antigen CD37; leukocyte antigen CD37; CD37 molecule; Tetraspanin-26; Tspan-26; CD_antigen: CD37]
  • Products gene name
    [CD37]
  • Other gene names
    [CD37; CD37; GP52-40; TSPAN26; TSPAN26; Tspan-26]
  • Clonality
    Monoclonal
  • Isotype
    IgG2b, kappa
  • Clone
    [IPO-24]
  • Host
    Mouse, Murine monoclonal antibodies or Mabs are often conjugated and the isotype is IgG.
  • Reactivity
    Human
  • Specificity
    Recognizes a protein of 33-55kDa, identified as CD37 (Workshop V; Code CD37.7). CD37 is strongly expressed on normal and neoplastic mature (sIg+) B-lymphocytes. In B-cell ontogeny, CD37 appears after the pre-B-cell stage, is maintained during peripheral B-cell development and is lost upon terminal differentiation into plasma cells.1 CD37 is also present, at low densities, on resting and activated T cells, neutrophils, monocytes, and some myelomonocytic leukemia cells. It is absent from platelets, erythrocytes. CD37 is a member of a family of tetraspan transmembrane proteins, including CD9, CD53, CD63, CD81, and CD82. It associates other tetraspan transmembrane proteins and MHC class II molecules to form a large complex at the surface of B cells and play a role in signal transduction. CD37 is a valuable and stable marker for peripheral mature B-cells and corresponding malignancies like B-cell chronic lymphocytic leukemia (B-CLL), hairy cell leukemia (HCL), and all types of B-cell non-Hodgkin's lymphoma (B-NHL).
  • Form
    200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
  • Storage stability
    Antibody with azide - store at 2 to 8 degree C. Antibody without azide - store at -20 to -80 degree C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
  • Tested application
    Functional Studies, Flow Cytometry (FC/FACS), Immunofluorescence (IF)
  • Alternative to gene target
    • [ "CD37 molecule", "GP52-40 and TSPAN26", "CD37 and IDBG-62489 and ENSG00000104894 and 951", "protein binding", "Cell surfaces", "Cd37 and IDBG-182311 and ENSMUSG00000030798 and 12493", "CD37 and IDBG-640486 and ENSBTAG00000011421 and 508751" ]
  • Gene target
    CD37 Peripheral Mature B Monoclonal
    • Gene info
  • Gene symbol
    CD37
  • isotype filter
    • IgG2b
    • kappa
  • Short name
    CD37 (Peripheral Mature B- ) Mouse Monoclonal Antibody
  • technique filter
    • Mouse monoclonal
    • Antibody
    • Mouse
  • Technique
    Mouse monoclonal, Antibody, Mouse, antibodies against human proteins, antibodies for, Component cell markers and DNA bp. markers are genetic markers er genes or DNA sequences with a known location on a chromosome that can be used to identify individuals or species. Protein markers in kDA. Monoclonals or monoclonal antibodies, mouses, mouse monoclonals
  • Alternative technique
    antibodies, murine
  • Tissue
    cell
  • tissue filter
    • cell