- Catalog numberMBS438590
- Product nameCD16 / Fc-gamma Receptor III Mouse Monoclonal Antibody
- Size0.1 mg (With BSA & Azide at 0.2mg/mL)
- PriceAsk For Price
- Products typeAntibody
- Products short name[CD16 / Fc-gamma Receptor III]
- Products name syn[FcRIIIa; FCR-10; FcRIII; FCGRIII; FcR-10; Fc fragment of IgG, low affinity IIIa, receptor for (CD16); neutrophil-specific antigen NA; CD16a; low affinity immunoglobulin gamma Fc region receptor III-A; Fc-gamma RIIIa; immunoglobulin G Fc receptor III; Fc-gamma RIII-alpha; Fc-gamma receptor IIIb (CD16); CD16a antigen; Fc-gamma receptor III-2 (CD 16); FCGR3; Fc gamma receptor III-A; FCG3; low affinity III, receptor for (CD16); Fc-gamma RIII; IGFR3FcgammaRIIIA; CD16FCRIIIA; FCRIII; Fc fragment of IgG, low affinity IIIa, receptor (CD16a)]
- Other names[low affinity immunoglobulin gamma Fc region receptor III-A isoform a; Low affinity immunoglobulin gamma Fc region receptor III-A; low affinity immunoglobulin gamma Fc region receptor III-A; Fc fragment of IgG receptor IIIa; CD16a antigen; Fc-gamma RIII-alpha; Fc-gamma RIII; Fc-gamma RIIIa; FcRIII; FcRIIIa; FcR-10; IgG Fc receptor III-2; CD_antigen: CD16a]
- Products gene name[FCGR3A]
- Other gene names[FCGR3A; FCGR3A; CD16; FCG3; CD16A; FCGR3; IGFR3; IMD20; FCR-10; FCRIII; FCGRIII; FCRIIIA; CD16A; FCG3; FCGR3; IGFR3; Fc-gamma RIII; Fc-gamma RIIIa; FcRIII; FcRIIIa]
- ClonalityMonoclonal
- IsotypeIgG2a, kappa
- Clone[HO-80]
- HostMouse, Murine monoclonal antibodies or Mabs are often conjugated and the isotype is IgG.
- ReactivityHuman. Others not tested
- SpecificityIt recognizes CD16 (Fc gamma RIII), the low-affinity receptor for IgG with an apparent molecular weight of 50-80kDa. Two similar genes represent CD16, CD16A (Fc gamma RIIIA), which exists as a hetero-oligomeric polypeptide-anchored form in macrophages and NK cells and CD16B (Fc gamma RIIIB), which exist as a monomeric GPI-anchored form in neutrophils. Furthermore, there are two known polymorphisms of CD16B, NA-1 and NA-2. Individuals homozygous for NA-2 show a lower phagocytic capacity compared with NA-1. CD16 binds IgG in the form of immune complexes and shows preferential binding of IgG1 and IgG3 isotypes and minimal binding of IgG2 and IgG4. Upon IgG binding, both CD16 isoforms initiate signal transduction cascades that lead to a variety of responses including antibody-dependent cell-mediated cytotoxicity (ADCC), phagocytosis, degranulation and proliferation.
- Form200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
- Storage stabilityAntibody with azide - store at 2 to 8 degree C. Antibody without azide - store at -20 to -80 degree C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- Tested applicationFunctional Studies, Flow Cytometry (FC/FACS), Immunofluorescence (IF)
- Gene targetCD16 / Fc-gamma Receptor III Monoclonal
- Identity:HGNC:27652
- Gene:CPLX3
- Long gene name:complexin 3
- Synonyms:CPX-III
- Discovery year:2005-08-02
- Entrez gene record:594855
- Pubmed identification:15911881
- RefSeq identity:NM_001030005
- VEGA ID:OTTHUMG00000142816
- Identity:HGNC:7046
- Gene:MGAT3
- Long gene name:beta-1,4-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase
- Synonyms gene name:mannosyl (beta-1,4-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase
- Synonyms:GNT-III
- Discovery year:1993-08-27
- Entrez gene record:4248
- Pubmed identification:8370666
- RefSeq identity:NM_002409
- Classification:Mannosyl-glycoprotein N-acetylglucosaminyltransferases
- VEGA ID:OTTHUMG00000030185
- Identity:HGNC:3619
- Gene:FCGR3A
- Long gene name:Fc gamma receptor IIIa
- Synonyms gene name:Fc fragment of IgG, low affinity IIIa, receptor for (CD16), Fc fragment of IgG, low affinity IIIa, receptor (CD16a), Fc fragment of IgG receptor IIIa
- Synonyms:CD16, CD16a, FcgammaRIIIaFcGRIIIA
- Discovery year:1988-11-30
- Entrez gene record:2214
- Pubmed identification:2139735, 11835346, 19309690
- RefSeq identity:NM_000569
- Classification:Immunoglobulin like domain containing, CD molecules
- VEGA ID:OTTHUMG00000034466
- Identity:HGNC:3620
- Gene:FCGR3B
- Long gene name:Fc gamma receptor IIIb
- Synonyms gene name:Fc fragment of IgG, low affinity IIIb, receptor for (CD16), Fc fragment of IgG, low affinity IIIb, receptor (CD16b), Fc fragment of IgG receptor IIIb
- Synonyms:CD16, CD16b, FcgammaRIIIbFcRIIIb
- Discovery year:1991-08-21
- Entrez gene record:2215
- Pubmed identification:2139735, 11034564, 17529978
- RefSeq identity:NM_000570
- Classification:CD molecules, Immunoglobulin like domain containing
- VEGA ID:OTTHUMG00000074099
- Identity:HGNC:30135
- Gene:P4HA3
- Long gene name:prolyl 4-hydroxylase subunit alpha 3
- Synonyms gene name:procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), alpha polypeptide III, prolyl 4-hydroxylase, alpha polypeptide III
- Synonyms:C-P4Halpha(III),
- Discovery year:2004-05-12
- Entrez gene record:283208
- Pubmed identification:14500733
- RefSeq identity:NM_182904
- VEGA ID:OTTHUMG00000165254
- Identity:HGNC:1506
- Gene:CASP5
- Long gene name:caspase 5
- Synonyms gene name:caspase 5, apoptosis-related cysteine protease, caspase 5, apoptosis-related cysteine peptidase
- Synonyms:ICE(rel)III,
- Discovery year:1996-09-13
- Entrez gene record:838
- Pubmed identification:7797592, 9250871
- RefSeq identity:NM_004347
- Classification:Caspases, Caspase recruitment domain containing
- VEGA ID:OTTHUMG00000048073
- Identity:HGNC:23187
- Gene:THAP4
- Long gene name:THAP domain containing 4
- Synonyms:CGI-36Nb(III)
- Discovery year:2003-10-08
- Entrez gene record:51078
- Pubmed identification:12575992, 10810093, 30524950
- RefSeq identity:NM_015963
- Classification:THAP domain containing
- VEGA ID:OTTHUMG00000133410
- Identity:HGNC:5709
- Gene:IGHVIII-82
- Long gene name:immunoglobulin heavy variable (III)-82 (pseudogene)
- Synonyms gene name:immunoglobulin heavy variable (III)-82, immunoglobulin heavy variable (III)-82 pseudogene
- Synonyms:IGHV(III)-82,
- Discovery year:2000-04-17
- Entrez gene record:28338
- RefSeq identity:NG_001019
- Classification:Immunoglobulin heavy locus at 14q32.33
- VEGA ID:OTTHUMG00000151732
- Identity:HGNC:7426
- Gene:MT-CSB3
- Long gene name:mitochondrially encoded conserved sequence block III
- Synonyms gene name:conserved sequence block III
- Synonyms:CSB-III
- Discovery year:1989-10-11
- Pubmed identification:2982153
- Classification:Mitochondrially encoded regions
- Gene symbolCPLX3, MGAT3, MGST3, FCGR3A, FCGR3B, P4HA3, CASP5, THAP4, IGHVIII-82, MT-CSB3
- isotype filter
- IgG2a
- kappa
- Short nameCD16 / Fc-gamma Receptor III Mouse Monoclonal Antibody
- technique filter
- Mouse monoclonal
- Antibody
- Mouse
- FC
- TechniqueMouse monoclonal, Antibody, Mouse, FC, antibodies against human proteins, antibodies for, Monoclonals or monoclonal antibodies, mouses, mouse monoclonals
- Alternative techniqueantibodies, murine
Gene info
Gene info
Gene info
Gene info
Locus Specific Databases:FCGR3Abase: Mutation registry for Natural killer cell deficiencyLRG_60
Gene info
Locus Specific Databases:LRG_1238