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Carcinoembryonic Antigen (CEA) Mouse Monoclonal Antibody (C234)

  • Catalog number
    MBS588366
  • Product name
    Carcinoembryonic Antigen (CEA) Mouse Monoclonal Antibody (C234)
  • Size
    5x0.1 mg
  • Products type
    Antibody
  • Products short name
    [Carcinoembryonic Antigen (CEA)]
  • Other names
    [carcinoembryonic antigen, partial; Carcinoembryonic antigen-related cell adhesion molecule 5; carcinoembryonic antigen-related cell adhesion molecule 5; carcinoembryonic antigen related cell adhesion molecule 5; Carcinoembryonic antigen; CEA; Meconium antigen 100; CD_antigen: CD66e]
  • Products gene name
    [CEA]
  • Other gene names
    [CEACAM5; CEACAM5; CEA; CD66e; CEA; CEA]
  • Clonality
    Monoclonal
  • Isotype
    IgG kappa
  • Clone
    [C234]
  • Host
    Mouse, Murine monoclonal antibodies or Mabs are often conjugated and the isotype is IgG.
  • Reactivity
    Human
  • Specificity
    This antibody is CEA specific. It does not recognize NCA, neither in enzyme linked immunosorbent assay (ELISA) not on Western blots of crude tissue extracts. This antibody binds to CEA producing human adenocarcinoma cells (e.g. LS174T,WiDr) but does not bind to CEA non-secreting human adenocarcinoma cells (Colo 320DM). It does not immunostain cryocuts of any normal human tissues tested (artery, heart muscle, kidney, large bowel, liver, lung, skeletal muscle, skin, small gut, spleen, testes or vein) neither does it react with any antigens on human blood cells when separated by fluoresceine actuated cell sorter (FACS). Immunohistochemical analysis of cancerous tissues revealed that the antibody bound selectively adenocarcinoma and not carcinoid tumor of the colon, as well as tumor-associated CEA in breast, gastric and lung neoplasms, while there was no immunohistochemical evidence of cross-reactivity with NCA. A remarkable feature of this antibody is its ability to distinguish immunohistochemically between cancer and residual normal tissue within the same organ.
  • Form
    Lyophilized Protein A purified in PBS pH7.4 (Full IgG)
  • Storage stability
    Lyophilized antibody can be kept at 4 degree C for up to 3 months and should be kept at-20 degree C for long-term storage. To avoid freeze-thaw cycles, reconstituted antibody should be aliquoted before freezing for short-term storage (-20 degree C) or for long-term storage (-80 degree C). For maximum recovery of product centrifuge the original vial prior to removing the cap. Further dilutions can be made in assay buffer.
  • Tested application
    ELISA (EIA), Immunohistochemistry (IHC)
  • Gene target
    Carcinoembryonic CEA Monoclonal C234
    • Gene info
    Gene info
    Gene info
  • Gene symbol
    CEACAM7, CEACAM5, PSG2
  • isotype filter
    • IgG kappa
  • Short name
    Carcinoembryonic Antigen (CEA) Mouse Monoclonal Antibody (C234)
  • technique filter
    • Mouse monoclonal
    • Antibody
    • antigen
    • Mouse
  • Technique
    Mouse monoclonal, Antibody, antigen, Mouse, antibodies against human proteins, antibodies for, antigenes, Monoclonals or monoclonal antibodies, mouses, mouse monoclonals
  • Alternative technique
    antibodies, antigenes, murine