- Catalog numberbs-9230R-FITC
- Product nameRNF158 Antibody, FITC Conjugated
- Size0.1ml
- PriceAsk For Price
- Short nameAnti-RNF158
- Long nameRNF158 Polyclonal Antibody, FITC Conjugated
- CategoryConjugated Primary Antibodies
- ConjugationFITC
- Host OrganismRabbit (Oryctolagus cuniculus)
- Target AntigenRNF158
- SpecificityThis is a highly specific antibody against RNF158.
- ModificationUnmodified
- Modification siteNone
- ClonalityPolyclonal
- ClonePolyclonal antibody
- IsotypeImmunoglobulin G (IgG)
- Concentration1ug per 1ul
- SourceKLH conjugated synthetic peptide derived from human RNF158
- Gene ID number153769
- Tested applicationsIF(IHC-P)
- Recommended dilutionsIF(IHC-P)(1:50-200)
- CrossreactivityHuman, Mouse, Rat
- Crossreactive species detailsDue to limited amount of testing and knowledge, not every possible cross-reactivity is known.
- Antigen backgroundThe RING-type zinc finger motif is present in a number of viral and eukaryotic proteins and is made of a conserved cysteine-rich domain that is able to bind two zinc atoms. Proteins that contain this conserved domain are generally involved in the ubiquitination pathway of protein degradation. SH3RF2 (SH3 domain containing ring finger 2), also known as RNF158, is a 729 amino acid protein with one RING-type zinc finger domain and three SH3 domains. Via its RING-type zinc finger domain, SH3RF2 binds an E2 ubiquitin-conjugating enzyme. This suggests that SH3RF2 functions as an E3 ubiquitin-protein ligase that accepts a ubiquitin residue from an E2 ubiquitin-conjugating enzyme and immediately transfers that residue to a protein that is targeted for degradation. Due to alternative splicing events, SH3RF2 is expressed as two different isoforms.
- Purification methodThis antibody was purified via Protein A.
- Storage conditionsKeep the antibody in an aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store refrigerated at 2 to 8 degrees Celcius for up to 1 year.
- Excitation Emission494nm/518nm
- SynonymsHeart protein phosphatase 1-binding protein; HEPP1; Putative E3 ubiquitin protein ligase SH3RF2; Putative E3 ubiquitin-protein ligase SH3RF2; RING finger protein 158; SH3 domain containing RING finger protein 2; SH3 domain-containing RING finger protein 2; SH3R2_HUMAN; Sh3rf2.
- Gene targetRNF158 Conjugated
- Identity:HGNC:26299
- Gene:SH3RF2
- Long gene name:SH3 domain containing ring finger 2
- Synonyms gene name:protein phosphatase 1, regulatory subunit 39
- Synonyms:FLJ23654RNF158Hepp1POSHER
- Discovery year:2004-03-05
- Entrez gene record:153769
- Pubmed identification:22128169
- RefSeq identity:NM_152550
- Classification:Protein phosphatase 1 regulatory subunits, Ring finger proteins
- VEGA ID:OTTHUMG00000129685
- Gene symbolSH3RF2
- isotype filter
- Immunoglobulin G IgG
- LabelFITC
- label filter
- FITC
- technique filter
- Antibody
- FITC
- TechniqueAntibody, FITC, antibodies against human proteins, antibodies for, antibody Conjugates, Fluorescein
- Alternative techniqueantibodies, fluorescine