- Catalog numberGEN211808
- Product nameMOUSE Anti-HUMAN CD227 Antibody
- Size200ug
- PriceAsk For Price
- Also known asCD227
- Other namesmucin-1 isoform 2; Mucin-1; mucin-1; episialin; DF3 antigen; H23 antigen; cancer antigen 15-3; krebs von den Lungen-6; mucin 1, transmembrane; tumor-associated mucin; carcinoma-associated mucin; polymorphic epithelial mucin; peanut-reactive urinary mucin; tumor associated epithelial mucin; breast carcinoma-associated antigen DF3; tumor-associated epithelial membrane antigen; mucin 1, cell surface associated; Breast carcinoma-associated antigen DF3; Cancer antigen 15-3; CA 15-3; Carcinoma-associated mucin; Episialin; H23AG; Krebs von den Lungen-6; KL-6; PEMT; Peanut-reactive urinary mucin; PUM; Polymorphic epithelial mucin; PEM; Tumor-associated epithelial membrane antigen; EMA; Tumor-associated mucin; CD_antigen: CD227Cleaved into the following 2 chains:Mucin-1 subunit alpha; MUC1-NT; MUC1-alpha; Mucin-1 subunit beta; MUC1-betaAlternative name(s):MUC1-CT
- CategoryAntibodies
- SubcategoryMnoclonal antibodies
- Gene nameCD227
- Gene name synonimsN/A
- Other gene namesMUC1; MUC1; EMA; PEM; PUM; KL-6; MAM6; PEMT; CD227; H23AG; MUC-1; CA 15-3; MUC-1/X; MUC1/ZD; MUC-1/SEC; PUM; MUC-1; CA 15-3; KL-6; PUM; PEM; EMA; MUC1-NT; MUC1-alpha; MUC1-beta
- ClonalityMonoclonal
- Immunoglobulin isotypeIgG1
- CloneVU-3C6
- Host organismMouse (Mus musculus)
- Species reactivityHuman (Homo sapiens); Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby.
- Specificity and cross reactivityCD227 Mucins are a family of high molecular weight, heavily glycosylated proteins (glycoconjugates) produced by many epithelial tissues in vertebrates. This item recognises CD227, also known as mucin 1 which is a breast cancer associated mucin encoded by the Muc-1 gene. CD227 is expressed on most secretory epithelium, including mammary gland and some hematopoietic cells. This protein is overexpressed abundantly in >90% breast carcinomas and metastases. The dominant epitope recognised by this antibody is the 12-mer GVTSAPDTRPAP of the mucin 1 tandem repeat. This item has been tested on frozen human ovarian carcinoma tissue sections and paraffin embedded sections from normal breast tissue. This antibody also reacts weakly with sections of small intestine and colon.; Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited. This particular antibody might cross react with speacies outside of the listed ones.
- Purification methodN/A
- Form AppearancePurified (Purified IgG - liquid)
- ConcentrationIgG concentration 1.0 mg/ml
- Storage and shippingStore the antibody at +4 degrees Celsius for short-term storage and at -20 degrees Celsius for long-term.Storage in frost-free freezers is not recommended. the antibody should be stored undiluted. Repeated freeze - thaw cycles may denature the peptide chains of the antibody and therefore should be maximally avoided. If there is a precipitate in the vial we recommend you to briefly microcentrifugate it prior to use. Shelf Life: 18 months from date of dispatch.
- Tested applicationsImmunohistology - Paraffin (IHC), Immunoprecipitation (IP), Flow Cytometry (FACS), Immunohistology - Frozen (IHC)
- Gene targetCD227
- Identity:HGNC:7508
- Gene:MUC1
- Long gene name:mucin 1, cell surface associated
- Synonyms gene name:mucin 1, transmembrane, medullary cystic kidney disease 1 (autosomal dominant)
- Synonyms:CD227, PEMADMCKDADMCKD1MCKDMCDKL-6EMACa15-3
- Discovery year:1986-01-01
- Entrez gene record:4582
- Pubmed identification:1697589, 23396133
- RefSeq identity:NM_002456
- Classification:CD molecules, Mucins
- VEGA ID:OTTHUMG00000035681
- Gene symbolMUC1
- Hostmouse
- Short nameMOUSE Anti- CD227 Antibody
- technique filter
- anti-Human
- Antibody
- anti-
- Mouse
- anti
- Techniqueanti-Human, Antibody, anti-, Mouse, anti, antibody to, antibodies, antibodies against human proteins, antibodies for, antibodies against human proteins, mouses
- Alternative techniqueantibodies, murine