- Catalog numberGEN212675
- Product nameHAMSTER ANTI MOUSE CD61 Antibody
- Size100ug
- PriceAsk For Price
- Also known asCD61
- Other namesintegrin beta-3; Integrin beta-3; integrin beta-3; GPIIIa; platelet gpIIIa; platelet membrane glycoprotein IIIa; integrin beta 3; Platelet membrane glycoprotein IIIa
- CategoryAntibodies
- SubcategoryMnoclonal antibodies
- Gene nameCD61
- Gene name synonimsN/A
- Other gene namesItgb3; Itgb3; CD61; GP3A; INGRB3; GPIIIa
- ClonalityMonoclonal
- Immunoglobulin isotypeIgG
- CloneHM beta 3.1
- Host organismHamster
- Species reactivityMouse (Mus musculus); Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby.
- Specificity and cross reactivityCD61 This item recognises the murine integrin beta 3 subunit (CD61), a 90kD a type I membrane protein, which is expressed primarily on megakaryocytes, platelets, monocytes, macrophages, granulocytes and endothelial cells. CD61 associates with either the alpha IIb integrin (CD41) or the alpha V integrin (CD51) to form the platelet glycoprotein complex IIb/IIIa and the vitronectin receptor (VNR) respectively. The heterodimers formed with CD61 are receptors for a variety of ligands including fibrinogen, fibronectin, von Willebrands factor (vWF), vitronectin and thrombospondin. Clone HM beta 3-1 is reported to partially inhibit the binding of CD61 to fibronectin; Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited. This particular antibody might cross react with speacies outside of the listed ones.
- Purification methodN/A
- Form AppearancePurified (Purified IgG - liquid)
- ConcentrationIgG concentration 1.0 mg/ml
- Storage and shippingStore the antibody at +4 degrees Celsius for short-term storage and at -20 degrees Celsius for long-term. the antibody should be stored undiluted. Storage in frost-free freezers is not recommended. Repeated freeze - thaw cycles may denature the peptide chains of the antibody and therefore should be maximally avoided. Shelf Life: 18 months from date of dispatch.
- Tested applicationsImmunoprecipitation (IP), Flow Cytometry (FACS)
- Gene targetCD61
- Identity:HGNC:6156
- Gene:ITGB3
- Long gene name:integrin subunit beta 3
- Synonyms gene name:integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)
- Synonyms:CD61GPIIIa
- Discovery year:1988-06-09
- Entrez gene record:3690
- Pubmed identification:2454952
- RefSeq identity:NM_000212
- Classification:CD molecules, Integrin beta subunits
- VEGA ID:OTTHUMG00000171956
- Gene symbolITGB3
- HostHamster
- Short nameANTI MOUSE CD61 Antibody
- technique filter
- anti mouse
- Antibody
- Mouse
- anti
- Techniqueanti mouse, Antibody, Mouse, anti, antibody to, anti mouse antibodies, antibodies against human proteins, antibodies for, mouses
- Alternative techniqueantibodies, murine
Gene info
Locus Specific Databases:LRG_481