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Solute Carrier Family 4 Anion Exchanger Member 1 (Erythrocyte Membrane protein Band 3 Diego Blood Group) (SLC4A1) Rabbit anti

  • Catalog number
    PKSR030244-100µg
  • Product name
    Recombinant Rat CD68 / Macrosialin Protein (His tag) 100µg
  • Size
    100µg
  • Synonym
    CD68
  • Activity
    NA
  • Sequence
    Met1-Ser295
  • Fusion tag
    C-His
  • Accession
    Q4FZY1
  • ExpressedHost
    HEK293 Cells
  • Shipping
    In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature.Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.
  • Purity
    > 95 % as determined by SDS-PAGE
  • Endotoxin
    < 1.0 EU per μg of the protein as determined by the LAL method
  • Stability and Storage
    Samples are stable for up to twelve months from date of receipt at -70℃.Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
  • Mol Mass
    30.9 kDa
  • AP Mol Mass
    66-90 KDa
  • Formulation
    Lyophilized from sterile PBS, pH 7.4
  • Background
    Macrosialin, also known as CD68 and Gp110, is a single-pass type I  membrane protein which belongs to the LAMP family. CD68 is highly expressed by blood monocytes and tissue macrophages. It is also expressed in lymphocytes, fibroblasts and endothelial cells. CD68 is expressed in many tumor cell lines which could allow them to attach to selectins on vascular endothelium, facilitating their dissemination to secondary sites. CD68 plays a role in phagocytic activities of tissue macrophages, both in intracellular lysosomal metabolism and extracellular cell-cell and cell-pathogen interactions. It is a commonly used marker for macrophages. However, a number of studies have shown that CD68 antibodies react with other hematopoietic and non-hematopoietic cell types, suggesting that CD68 may not be a macrophage-specific antigen. CD68 binds to tissue- and organ-specific lectins or selectins, allowing homing of macrophage subsets to particular sites. Rapid recirculation of CD68 from endosomes and lysosomes to the plasma membrane may allow macrophages to crawl over selectin-bearing substrates or other cells.
  • Technical Data
    Technical_Data
  • Alternative to gene target
    • [ "CD68 molecule", "GP110 and LAMP4 and SCARD1", "CD68 and IDBG-25923 and ENSG00000129226 and 968", "Plasma membranes", "Cd68 and IDBG-191443 and ENSMUSG00000018774 and 12514", "CD68 and IDBG-635034 and ENSBTAG00000000133 and 504960" ]
  • Gene target
    CD68 / Macrosialin Protein His tag 100µg
    • Gene info
  • Gene symbol
    CD68
  • Host
    Rat
  • Short name
    Recombinant CD68 / Macrosialin Protein (His tag) 100µg
  • Label
    His
  • label filter
    • His
  • technique filter
    • Recombinant
  • Technique
    Recombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. Elabscience advises they will be reconstituted in a buffer soluion or culture medium for cell culture. Tags
  • Alternative technique
    rec