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50X TAE Buffer, Refill Pack

  • Catalog number
    bs-7034R-Cy5
  • Product name
    Eph receptor A7 Antibody, Cy5 Conjugated
  • Size
    0.1ml
  • Short name
    Anti-EphA7
  • Long name
    Eph receptor A7 Polyclonal Antibody, Cy5 Conjugated
  • Category
    Conjugated Primary Antibodies
  • Conjugation
    Cy5
  • Host Organism
    Rabbit (Oryctolagus cuniculus)
  • Target Antigen
    EphA7
  • Specificity
    This is a highly specific antibody against EphA7. There is a chance that this protein will cross-react with EphA4 based on a 73% non-sequential sequence similarity.
  • Modification
    Unmodified
  • Modification site
    None
  • Clonality
    Polyclonal
  • Clone
    Polyclonal antibody
  • Isotype
    Immunoglobulin G (IgG)
  • Concentration
    1ug per 1ul
  • Immunogen range
    203-253/998
  • Subcellular location
    Extracellular
  • Source
    KLH conjugated synthetic peptide derived from human EphA7
  • Gene ID number
    2045
  • Swiss Prot
    Q15375
  • Tested applications
    FCM, IF(IHC-P)
  • Recommended dilutions
    FCM(1:20-100), IF(IHC-P)(1:50-200)
  • Crossreactivity
    Human, Mouse, Rat
  • Crossreactive species details
    Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
  • Antigen background
    Receptor tyrosine kinase which binds promiscuously GPI-anchored ephrin-A family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. Among GPI-anchored ephrin-A ligands, EFNA5 is a cognate/functional ligand for EPHA7 and their interaction regulates brain development modulating cell-cell adhesion and repulsion. Has a repellent activity on axons and is for instance involved in the guidance of corticothalamic axons and in the proper topographic mapping of retinal axons to the colliculus. May also regulate brain development through a caspase(CASP3)-dependent proapoptotic activity. Forward signaling may result in activation of components of the ERK signaling pathway including MAP2K1, MAP2K2, MAPK1 AND MAPK3 which are phosphorylated upon activation of EPHA7.
  • Purification method
    This antibody was purified via Protein A.
  • Storage conditions
    Keep the antibody in an aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store refrigerated at 2 to 8 degrees Celcius for up to 1 year.
  • Excitation Emission
    625,650nm/670nm
  • Synonyms
    EHK3; EK11; EHK-3; HEK11; Ephrin type-A receptor 7; EPH homology kinase 3; EPH-like kinase 11; EPHA7
  • Gene target
    Eph receptor A7 Conjugated
  • isotype filter
    • Immunoglobulin G IgG
  • Label
    Cy5
  • label filter
    • Cy5
  • technique filter
    • Antibody
  • Technique
    Antibody, antibodies against human proteins, antibodies for, antibody Conjugates
  • Alternative technique
    antibodies