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Rabbit Lap3 antibody

  • Catalog number
    bs-5380R
  • Product name
    NMDAR2B (Tyr1252) Antibody
  • Size
    0.1ml
  • Short name
    Anti-NMDAR2B Tyr1252
  • Long name
    NMDAR2B (Tyr1252) Primary Polyclonal Antibody
  • Also known as
    NMDAR2B (Tyr1252) PAb
  • Category
    Primary Antibodies
  • Conjugation
    Unconjugated
  • Host
    Rabbit (Oryctolagus cuniculus)
  • Target Antigen
    NMDAR2B Tyr1252
  • Specificity
    This is a highly specific antibody against NMDAR2B Tyr1252. This antibody may cross react with NMDAR2A (Tyr 1246) due to 75% sequence similarity.
  • Modification s
    Phosphorylation
  • Modification site s
    Tyr1252
  • Clonality
    Polyclonal antibody
  • Clone number
    Polyclonal antibody
  • Isotype
    Immunoglobulin G (IgG)
  • Concentration
    1ug per 1ul
  • Immunogen range
    1230-1280/1484
  • Subcellular location
    Cytoplasm
  • Source
    KLH conjugated synthetic phosphopeptide derived from human NMDAR2B around the phosphorylation site of Tyr1252
  • Gene ID number
    2904
  • Swiss Prot
    Q13224
  • Tested Applications
    WB, IHC-P, IF(IHC-P)
  • Recommended dilutions
    WB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)
  • Cross reactivity
    Human, Mouse, Rat
  • Cross reactive species details
    Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
  • Background of the target antigen
    NMDA receptor subtype of glutamate-gated ion channels with high calcium permeability and voltage-dependent sensitivity to magnesium. Mediated by glycine. In concert with DAPK1 at extrasynaptic sites, acts as a central mediator for stroke damage. Its phosphorylation at Ser-1303 by DAPK1 enhances synaptic NMDA receptor channel activity inducing injurious Ca2+ influx through them, resulting in an irreversible neuronal death (By similarity).
  • Purification method
    This antibody was purified via Protein A.
  • Storage conditions
    Keep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
  • Synonym names
    MRD6; NR2B; hNR3; GluN2B; NMDAR2B; Glutamate receptor ionotropic, NMDA 2B; Glutamate [NMDA] receptor subunit epsilon-2; N-methyl D-aspartate receptor subtype 2B; N-methyl-D-aspartate receptor subunit 3; NR3; GRIN2B
  • Gene target
    NMDAR2B Tyr1252
    • Gene info
  • Gene symbol
    GRIN2B
  • isotype filter
    • Immunoglobulin G IgG
  • technique filter
    • Antibody
  • Technique
    Antibody, antibodies against human proteins, antibodies for
  • Alternative technique
    antibodies