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CD358 / DR6 / TNFRSF21 monoclonal antibody

  • Catalog number
    11-404-C100
  • Product name
    CD358 / DR6 / TNFRSF21 monoclonal antibody
  • Size
    100ug
  • Short name
    Anti-CD358 / DR6 / TNFRSF21 Mab
  • Long name
    Mouse Monoclonal Antibody against Human CD358 / DR6 / TNFRSF21, Clone: DR-6-04-EC
  • Antigen
    CD358 / DR6
  • Host
    Mouse (Mus musculus)
  • Species reactivity
    Human (Homo sapiens)
  • Negative species reactivity
    at the time of upload there has been no data, please, contact us to obtain most recent information on species reactivity and cross reactivity
  • Clonality
    Monoclonal Antibody (Mab)
  • Clone
    DR-6-04-EC
  • Isotype
    IgG1
  • Applications
    FC, IP, ICC
  • Immunogen
    A fusion protein representing amino acids 42-335 (extracellular part) of human DR6 linked to the Fc portion of human IgG1 was used as an immunogen.
  • Format conjugation
    purified; unconjugated
  • Specificity
    The antibody DR-6-04-EC recognizes human DR6 (Death receptor-6), a type I transmembrane protein containing cytoplasmic death domain, widely expressed in most human tissues and cell lines._x000D_
  • Research area
    CD and Related Antigens (Human), Apoptosis (Human), Apoptosis
  • Concentration
    1 mg/ml
  • Storage buffer
    Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.4
  • Shipping and storage
    Mouse Monoclonal Antibody against Human CD358 / DR6 / TNFRSF21, Clone: DR-6-04-EC is transported on blue ice/ice packs and should be stored at temperatures between 1 and 5 degrees Celsius. Do not freeze! Avoid exposing the product to direct light, especially the conjugated antibodies as most conjugates are very sentitive to light.
  • Background
    CD358 / DR6 (Death Receptor-6) is a type I transmembrane protein of the TNF receptor superfamily, expressed in most human tissues and able of inducing apoptosis through its cytoplasmic death domain. Unlike TNFR1 and Fas, DR6 induces apoptosis independently of FADD adaptor. In immune system, DR6 serves as an important regulator for CD4+ T cell proliferation and Th differentiation, and provides also a regulatory mechanism for B cell activation and humoral immune responses.
  • Purity
    > 95% (by SDS-PAGE)
  • Purification method
    Purified by protein-A affinity chromatography
  • Datasheet
    Datasheet
  • References
    Contact us for the most recent list of references
  • Alternative to gene target
    • [ "tumor necrosis factor receptor superfamily, member 21", "TNFRSF21 and IDBG-90063 and ENSG00000146072 and 27242", "protein binding", "Plasma membranes", "Tnfrsf21 and IDBG-184035 and ENSMUSG00000023915 and 94185", "TNFRSF21 and IDBG-632394 and ENSBTAG00000020054 and 537922" ]
  • Gene target
    CD358 / DR6 / TNFRSF21 monoclonal
    • Gene info
  • Gene symbol
    TNFRSF21
  • isotype filter
    • IgG1
  • technique filter
    • Antibody
  • Technique
    Antibody, antibodies against human proteins, antibodies for, Monoclonals or monoclonal antibodies
  • Alternative technique
    antibodies