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CD326 / EpCAM monoclonal antibody

  • Catalog number
    T7-581-T100
  • Product name
    CD326 / EpCAM monoclonal antibody
  • Size
    100 assays
  • Short name
    Anti-CD326 / EpCAM Mab
  • Long name
    Mouse Monoclonal Antibody against Human CD326 / EpCAM, Clone: VU-1D9
  • Antigen
    CD326 / EpCAM
  • Host
    Mouse (Mus musculus)
  • Species reactivity
    Human (Homo sapiens), Other species Not tested
  • Negative species reactivity
    at the time of upload there has been no data, please, contact us to obtain most recent information on species reactivity and cross reactivity
  • Clonality
    Monoclonal Antibody (Mab)
  • Clone
    VU-1D9
  • Isotype
    IgG1
  • Applications
    FC, IHC(P), IP, WB, IHC(F), ICC
  • Immunogen
    Small cell lung carcinoma cell line H69.
  • Format conjugation
    PE-Cy 7
  • Specificity
    The mouse monoclonal antibody VU-1D9 recognizes an epitope within EGF-like domain I of CD326 / EpCAM, a marker of epithelial lineages. This antibody strongly stains various normal epithelial cells and carcinomas.
  • Research area
    CD and Related Antigens (Human)
  • Storage buffer
    The reagent is provided in stabilizing phosphate buffered saline (PBS) solution containing 15mM sodium azide.
  • Shipping and storage
    Mouse Monoclonal Antibody against Human CD326 / EpCAM, Clone: VU-1D9 is transported on blue ice/ice packs and should be stored at temperatures between 1 and 5 degrees Celsius. Do not freeze! Avoid exposing the product to direct light, especially the conjugated antibodies as most conjugates are very sentitive to light.
  • Background
    CD326 / EpCAM (also known as ESA, EGP40, EGP-2, KSA1/4, CO17-1A, GA733-2, MOC31, Ber-EP4) is a 40 kDa transmembrane glycoprotein serving as adhesion molecule in the basolateral membranes in a variety of epithelial cells. CD326 mediates calcium-independent homotypic cell-cell adhesions. CD326 over-expression has been detected in many epithelial tumours and is often associated with bad prognosis. It has been used for diagnostics of (pre-) malignancies at early stages.
  • Purity
    > 95% (by SDS-PAGE)
  • Purification method
    Purified by affinity chromatography
  • Datasheet
    Datasheet
  • References
    *Brunner A, Prelog M, Verdorfer I, Tzankov A, Mikuz G, Ensinger C: EpCAM is predominantly expressed in high grade and advanced stage urothelial carcinoma of the bladder. J Clin Pathol. 2008 Mar;61(3):307-10., *Winter MJ, Nagtegaal ID, van Krieken JH, Litvinov SV: The epithelial cell adhesion molecule (Ep-CAM) as a morphoregulatory molecule is _x000D_ a tool in surgical pathology. Am J Pathol. 2003 Dec;163(6):2139-48., *Li G, Passebosc-Faure K, Lambert C, Gentil-Perret A, Blanc F, Oosterwijk E, Mosnier JF, Genin C, Tostain J: Flow cytometric analysis of antigen expression in malignant and normal renal cells. Anticancer Res. 2000 Jul-Aug;20(4):2773-8., *Ogura E, Senzaki H, Yoshizawa K, Hioki K, Tsubura A: Immunohistochemical localization of epithelial glycoprotein EGP-2 and_x000D_ carcinoembryonic antigen in normal colonic mucosa and colorectal tumors. Anticancer Res. 1998 Sep-Oct;18(5B):3669-75., *Tsubura A, Senzaki H, Sasaki M, Hilgers J, Morii S: Immunohistochemical demonstration of breast-derived and/or carcinoma-associated_x000D_ glycoproteins in normal skin appendages and their tumors. J Cutan Pathol. 1992 Feb;19(1):73-9._x000D_
  • Alternative to gene target
    • [ "epithelial cell adhesion molecule", "DIAR5 and EGP-2 and EGP314 and EGP40 and ESA and HNPCC8 and KS1/4 and KSA and M4S1 and MIC18 and MK-1 and TACSTD1 and TROP1", "EPCAM and IDBG-50831 and ENSG00000119888 and 4072", "protein complex binding", "Cell surfaces", "Epcam and IDBG-201437 and ENSMUSG00000045394 and 17075", "EPCAM and IDBG-633617 and ENSBTAG00000006474 and 514039" ]
  • Gene target
    CD326 / EpCAM monoclonal
    • Gene info
    Locus Specific Databases:Global Variome shared LOVDLRG_215
  • Gene symbol
    EPCAM
  • isotype filter
    • IgG1
  • technique filter
    • Antibody
  • Technique
    Antibody, antibodies against human proteins, antibodies for, Monoclonals or monoclonal antibodies
  • Alternative technique
    antibodies