- Catalog numberCSB-PA005282LD01HU_100ug
- Product nameRabbit Anti Human CFLAR Antibody-Biotin
- Size100ug
- PriceAsk For Price
- Long nameRabbit Antibody against Human CFLAR, Biotin
- Short nameAnti-CFLAR
- Synonym nameCFLAR Human Antibody
- HostRabbit, Rabbits
- Species reactivityHuman
- Tested applications recommended dilutionsELISA
- ConjugationBiotin
- Antibody isotypeIgG
- UniProt IDO15519
- FormatLiquid, diluted in buffer
- Buffer compositionPreservative: 0.03% Proclin 300, Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
- Purity>95%
- Purification methodProtein G purified
- Antibody categoryPolyclonal Antibodies
- Immunogen typeRecombinant human CASP8 and FADD-like apoptosis regulator protein (1-250AA)
- Immunogen speciesHuman
- AliasCASP8 and FADD-like apoptosis regulator,CFLAR,CASH,CASP8AP1,CLARP,MRIT,Caspase homolog,CASH,Caspase-eight-related protein,Casper,Caspase-like apoptosis regulatory protein,CLARP,Cellular FLICE-like inhibitory protein,c-FLIP,FADD-like antiapoptotic molecule 1,FLAME-1,Inhibitor of FLICE,I-FLICE,MACH-related inducer of toxicity,MRIT,Usurpin,CASP8 and FADD-like apoptosis regulator subunit p43,CASP8 and FADD-like apoptosis regulator subunit p12
- BackgroundApoptosis regulator protein which may function as a crucial link between cell survival and cell death pathways in mammalian cells. Acts as an inhibitor of TNFRSF6 mediated apoptosis. A proteolytic fragment (p43) is likely retained in the death-inducing signaling complex (DISC) thereby blocking further recruitment and processing of caspase-8 at the complex. Full length and shorter isoforms have been shown either to induce apoptosis or to reduce TNFRSF-triggered apoptosis. Lacks enzymatic (caspase) activity.
- ClonalityPolyclonal antibody
- Shipping and storageCFLAR Antibody is shipped on ice packs and upon receipt should be stored at -20 or -80 degrees Celsius. We recommend that you prepare the working aliquots in advance so that freez-thaw cycles are avoided. Do not expose the antibodies to drirect bright light, especially the labeled ones as most conjugates are light sensitive.
- Alternative to gene target
- [ "CASP8 and FADD-like apoptosis regulator", "c-FLIP and c-FLIPL and c-FLIPR and c-FLIPS and CASH and CASP8AP1 and Casper and CLARP and FLAME and FLAME-1 and FLAME1 and FLIP and I-FLICE and MRIT", "CFLAR and IDBG-78386 and ENSG00000003402 and 8837", "death effector domain binding", "Plasma membranes", "FLIP and IDBG-643202 and ENSBTAG00000010998 and 497199" ]
- Gene targetCFLAR -
- Identity:HGNC:14437
- Gene:CFLAR-AS1
- Long gene name:CFLAR antisense RNA 1
- Synonyms gene name:amyotrophic lateral sclerosis 2 (juvenile) chromosome region, candidate 10, CFLAR antisense RNA 1 (non-protein coding)
- Discovery year:2001-01-26
- Entrez gene record:65072
- Pubmed identification:27855375
- RefSeq identity:NR_040030
- Classification:Antisense RNAs
- VEGA ID:OTTHUMG00000154713
- Identity:HGNC:1876
- Gene:CFLAR
- Long gene name:CASP8 and FADD like apoptosis regulator
- Synonyms gene name:CASP8 and FADD-like apoptosis regulator
- Synonyms:CASHCasperCLARPFLAMEFLIPI-FLICEMRITc-FLIPcFLIP
- Discovery year:1999-05-07
- Entrez gene record:8837
- Pubmed identification:9208847, 9217161
- RefSeq identity:NM_003879
- Classification:Receptor ligands, Death effector domain containing, Death inducing signaling complex, Ripoptosome
- VEGA ID:OTTHUMG00000132819
- Gene symbolCFLAR-AS1, CFLAR
- LabelBiotin
- label filter
- Biotin
- technique filter
- anti human
- Antibody
- Rabbit
- anti
- Techniqueanti human, Antibody, Rabbit, anti, antibody to, anti human antibodies, antibodies against human proteins, antibodies for
- Alternative techniqueantibodies, rabbit-anti