• Catalog number
    PKSR030283-100µg
  • Product name
    Recombinant Rat CLEC5A / MDL1 / MDL-1 Protein (His tag) 100µg
  • Size
    100µg
  • Synonym
    CLEC5A
  • Activity
    NA
  • Sequence
    Val30-Lys190
  • Fusion tag
    N-His
  • Accession
    F7GAV1
  • ExpressedHost
    HEK293 Cells
  • Shipping
    In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature.Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.
  • Purity
    > 95 % as determined by SDS-PAGE
  • Endotoxin
    < 1.0 EU per μg of the protein as determined by the LAL method
  • Stability and Storage
    Samples are stable for up to twelve months from date of receipt at -70℃.Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
  • Mol Mass
    20.6 kDa
  • AP Mol Mass
    36 KDa
  • Formulation
    Lyophilized from sterile PBS, pH 7.4
  • Background
    CLEC5A, also known as MDL1 and MDL-1, is a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. Members of this family share a common protein fold and have diverse functions, such as cell adhesion, cell-cell signalling, glycoprotein turnover, and roles in inflammation and immune response. CLEC5A with dnax-activation protein 12 and may play a role in cell activation. It also functions as a positive regulator of osteoclastogenesis. CLEC5A acts as a key regulator of synovial injury and bone erosion during autoimmune joint inflammation .The binding of dengue virus to CLEC5A triggers signaling through the phosphylation of TYROBP, this interaction does not result in viral entry, but stimulates proinflammatory cytokine release.
  • Technical Data
  • Alternative to gene target
    • [ "C-type lectin domain family 5, member A", "CLECSF5 and MDL-1 and MDL1", "CLEC5A and IDBG-546985 and ENSG00000258227 and 23601", "carbohydrate binding", "Cell surfaces", "Clec5a and IDBG-139294 and ENSMUSG00000029915 and 23845", "CLEC5A and IDBG-636542 and ENSBTAG00000020453 and 615201" ]
  • Gene target
    CLEC5A / MDL1 / MDL-1 Protein His tag 100µg
  • Gene info
    Gene info
    Gene info
    Gene info
    Gene info
    Gene info
    Gene info
    Gene info
    Gene info
  • Gene symbol
    CLEC5A, IGHVII-1-1, MIR1-1, TRUND-NNN8-1, TRUND-NNN7-1, IGKV1OR2-1, MIR101-1, MIR1289-1, MIR16-1
  • Host
    Rat
  • Short name
    Recombinant CLEC5A / MDL1 / MDL-1 Protein (His tag) 100µg
  • Label
    His
  • label filter
    • His
  • technique filter
    • Recombinant
  • Technique
    Recombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. Elabscience advises they will be reconstituted in a buffer soluion or culture medium for cell culture. Tags
  • Alternative technique
    rec