- Catalog numberPKSR030283-100µg
- Product nameRecombinant Rat CLEC5A / MDL1 / MDL-1 Protein (His tag) 100µg
- Size100µg
- PriceAsk For Price
- SynonymCLEC5A
- ActivityNA
- SequenceVal30-Lys190
- Fusion tagN-His
- AccessionF7GAV1
- ExpressedHostHEK293 Cells
- ShippingIn general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature.Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.
- Purity> 95 % as determined by SDS-PAGE
- Endotoxin< 1.0 EU per μg of the protein as determined by the LAL method
- Stability and StorageSamples are stable for up to twelve months from date of receipt at -70℃.Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
- Mol Mass20.6 kDa
- AP Mol Mass36 KDa
- FormulationLyophilized from sterile PBS, pH 7.4
- BackgroundCLEC5A, also known as MDL1 and MDL-1, is a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. Members of this family share a common protein fold and have diverse functions, such as cell adhesion, cell-cell signalling, glycoprotein turnover, and roles in inflammation and immune response. CLEC5A with dnax-activation protein 12 and may play a role in cell activation. It also functions as a positive regulator of osteoclastogenesis. CLEC5A acts as a key regulator of synovial injury and bone erosion during autoimmune joint inflammation .The binding of dengue virus to CLEC5A triggers signaling through the phosphylation of TYROBP, this interaction does not result in viral entry, but stimulates proinflammatory cytokine release.
- Technical Data
- Alternative to gene target
- [ "C-type lectin domain family 5, member A", "CLECSF5 and MDL-1 and MDL1", "CLEC5A and IDBG-546985 and ENSG00000258227 and 23601", "carbohydrate binding", "Cell surfaces", "Clec5a and IDBG-139294 and ENSMUSG00000029915 and 23845", "CLEC5A and IDBG-636542 and ENSBTAG00000020453 and 615201" ]
- Gene targetCLEC5A / MDL1 / MDL-1 Protein His tag 100µg
- Identity:HGNC:2054
- Gene:CLEC5A
- Long gene name:C-type lectin domain containing 5A
- Synonyms gene name:C-type (calcium dependent, carbohydrate-recognition domain) lectin, superfamily member 5, C-type lectin domain family 5, member A, C-type lectin domain family 5 member A
- Synonyms:MDL-1,
- Discovery year:1999-10-19
- Entrez gene record:23601
- Pubmed identification:10449773
- RefSeq identity:NM_013252
- Classification:C-type lectin domain containing
- VEGA ID:OTTHUMG00000157173
- Identity:HGNC:5670
- Gene:IGHVII-1-1
- Long gene name:immunoglobulin heavy variable (II)-1-1 (pseudogene)
- Synonyms gene name:immunoglobulin heavy variable (II)-1-1, immunoglobulin heavy variable (II)-1-1 pseudogene
- Synonyms:IGHV(II)-1-1,
- Discovery year:2000-04-17
- Entrez gene record:28377
- RefSeq identity:NG_001019
- Classification:Immunoglobulin heavy locus at 14q32.33
- VEGA ID:OTTHUMG00000152325
- Identity:HGNC:31499
- Gene:MIR1-1
- Long gene name:microRNA 1-1
- Synonyms:hsa-mir-1-1
- Discovery year:2004-04-23
- Entrez gene record:406904
- RefSeq identity:NR_029780
- Classification:MicroRNA MIR1/206 family
- Identity:HGNC:50820
- Gene:TRUND-NNN8-1
- Long gene name:tRNA-undetermined (NNN) 8-1
- Synonyms gene name:transfer RNA-undetermined (NNN) 8-1
- Discovery year:2014-06-20
- Entrez gene record:103482528
- Pubmed identification:18984615
- Identity:HGNC:50819
- Gene:TRUND-NNN7-1
- Long gene name:tRNA-undetermined (NNN) 7-1
- Synonyms gene name:transfer RNA-undetermined (NNN) 7-1
- Discovery year:2014-06-20
- Entrez gene record:103482531
- Pubmed identification:18984615
- Identity:HGNC:5760
- Gene:IGKV1OR2-1
- Long gene name:immunoglobulin kappa variable 1/OR2-1 (pseudogene)
- Synonyms gene name:immunoglobulin kappa variable 1/OR-1, immunoglobulin kappa variable 1/OR-1 pseudogene, immunoglobulin kappa variable 1/OR-1 (pseudogene)
- Synonyms:IGKV1/OR-1, IGKV1/OR2-1,
- Discovery year:2000-04-18
- Entrez gene record:3531
- Pubmed identification:2853098
- Classification:Immunoglobulin kappa (IGK) orphons
- VEGA ID:OTTHUMG00000155081
- Identity:HGNC:31488
- Gene:MIR101-1
- Long gene name:microRNA 101-1
- Synonyms:hsa-mir-101-1
- Discovery year:2004-04-23
- Entrez gene record:406893
- RefSeq identity:NR_029516
- Classification:MicroRNA MIR101 family
- Identity:HGNC:35281
- Gene:MIR1289-1
- Long gene name:microRNA 1289-1
- Synonyms:hsa-mir-1289-1
- Discovery year:2008-11-03
- Entrez gene record:100302125
- RefSeq identity:NR_031620
- Classification:MicroRNA MIR1289 family
- Identity:HGNC:31545
- Gene:MIR16-1
- Long gene name:microRNA 16-1
- Synonyms:hsa-mir-16-1
- Discovery year:2004-04-23
- Entrez gene record:406950
- RefSeq identity:NR_029486
- Classification:MicroRNA MIR15/16 family
- Gene symbolCLEC5A, IGHVII-1-1, MIR1-1, TRUND-NNN8-1, TRUND-NNN7-1, IGKV1OR2-1, MIR101-1, MIR1289-1, MIR16-1
- HostRat
- Short nameRecombinant CLEC5A / MDL1 / MDL-1 Protein (His tag) 100µg
- LabelHis
- label filter
- His
- technique filter
- Recombinant
- TechniqueRecombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. Elabscience advises they will be reconstituted in a buffer soluion or culture medium for cell culture. Tags
- Alternative techniquerec