- Catalog numberPKSM040901-50µg
- Product nameRecombinant Mouse CD32 / FCGR2B Protein (His & AVI tag)
- Size50µg
- PriceAsk For Price
- SynonymAI528646;CD32;F630109E10Rik;Fcgr2;Fcgr2a;FcgRII;Fcr-2;Fcr-3;fcRII;Fc[g]RII;Ly-17;Ly-m20;LyM-1
- ActivityImmobilized mouse CD32-AVI-His at 10 μg/ml (100 μl/well) can bind biotinylated Human IgG1, The EC50 of biotinylated Human IgG1 is 0.08-0.18 μg/ml.
- SequenceMet 1-Arg 217
- Fusion tagC-His & AVI
- AccessionNP_001070657.1
- Expressed HostHEK293 Cells
- ShippingIn general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature.Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.
- Purity> 98 % as determined by SDS-PAGE
- Endotoxin< 1.0 EU per μg of the protein as determined by the LAL method
- Stability and StorageSamples are stable for up to twelve months from date of receipt at -70℃.Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
- Mol Mass23.9 kDa
- AP Mol Mass38-43 kDa
- FormulationLyophilized from sterile PBS, pH 7.4
- BackgroundReceptors for Fc portion of IgG (Fcγ Rs) are members of the Ig superfamily, and are divided into three classes designated Fcγ RI (CD64), Fcγ RII (CD32), and Fcγ RIII (CD16). CD32 protein is a low affinity receptor for IgG that binds only IgG immune complexes and is expressed on a diverse range of cells such as monocytes, macrophages, neutrophils, eosinophils, platelets, and B cells. Human CD32 class is encoded by three closely related genes, and designated Fcγ RII A, B, and C which share 94-99% amino acid identity in their extracellular domains but differ substantially in their transmembrane and cytoplasmic domains. CD32 is involved in a number of immune responses including antibody-dependent cell-mediated cytotoxicity, clearance of immune complexes, release of inflammatory mediators, and regulation of antibody production.
- Technical data
- Alternative to gene target
- [ "Fc fragment of IgG, low affinity IIb, receptor (CD32)", "CD32 and CD32B and FCG2 and FCGR2 and IGFR2", "FCGR2B and IDBG-104308 and ENSG00000072694 and 2213", "IgG binding", "Plasma membranes" ]
- Gene targetCD32 / FCGR2B Protein His AVI tag
- Identity:HGNC:3618
- Gene:FCGR2B
- Long gene name:Fc gamma receptor IIb
- Synonyms gene name:Fc fragment of IgG, low affinity IIb, receptor for (CD32), Fc fragment of IgG, low affinity IIb, receptor (CD32), Fc fragment of IgG receptor IIb
- Synonyms:CD32, CD32B, FcgammaRIIbFcGRIIB
- Discovery year:1991-08-21
- Entrez gene record:2213
- Pubmed identification:2139735, 19309690
- RefSeq identity:NM_004001
- Classification:CD molecules, Immunoglobulin like domain containing
- VEGA ID:OTTHUMG00000034470
- Identity:HGNC:3616
- Gene:FCGR2A
- Long gene name:Fc gamma receptor IIa
- Synonyms gene name:Fc fragment of IgG, low affinity IIa, receptor for (CD32), Fc fragment of IgG, low affinity IIa, receptor (CD32), Fc fragment of IgG receptor IIa
- Synonyms:CD32, CD32A, IGFR2CDw32Fc-gamma-RIIaFcgammaRIIa
- Discovery year:1988-11-30
- Entrez gene record:2212
- Pubmed identification:2139735, 8994865
- RefSeq identity:NM_021642
- Classification:Immunoglobulin like domain containing, CD molecules
- VEGA ID:OTTHUMG00000034469
- Gene symbolFCGR2B, FCGR2A
- Hostmouse
- Short nameRecombinant Mouse CD32 / FCGR2B Protein (His & AVI tag)
- LabelHis
- label filter
- His
- technique filter
- Recombinant
- Mouse
- TechniqueRecombinant, Mouse, mouses, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. Elabscience advises they will be reconstituted in a buffer soluion or culture medium for cell culture. Tags
- Alternative techniquerec, murine
Gene info
Gene info
Locus Specific Databases:LRG_1109