- Catalog numberPKSM040801-100µg
- Product nameRecombinant Mouse CD200R1 / OX-2R Protein (His tag) 100µg
- Size100µg
- PriceAsk For Price
- ActivityMeasured by its ability to bind mouse CD200 in a functional ELISA.
- SynonymCD200R;Mox2r;OX2R
- SequenceMet 1-Pro 238
- Fusion tagC-His
- AccessionNP_067300.1
- Expressed HostHEK293 Cells
- ShippingIn general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature.Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.
- Purity> 90 % as determined by SDS-PAGE
- Endotoxin< 1.0 EU per μg of the protein as determined by the LAL method
- Stability and StorageSamples are stable for up to twelve months from date of receipt at -70℃.Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
- Mol Mass24.6 kDa
- AP Mol Mass55-65 kDa
- FormulationLyophilized from sterile PBS, pH 7.4
- BackgroundThe cluster of differentiation (CD) system is commonly used as cell markers in immunophynotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules which associating with the immune function of the cell. There are more than 320 CD unique clusters and subclusters have been identified. Some of the CD molecules serve as receptors or ligands important to the cell through initiating a signal cascade which then alter the behavior of the cell. Some CD proteins do not take part in cell signal process but have other functions such as cell adhesion. Cell surface glycoprotein CD200 receptor 1 (CD200R1) is an isoform of CD200 receptors which is expressed on cells of the myeloid lineage. CD200R1 is a receptor for the OX-2 membrane glycoprotein. The receptor-substrate interaction may serve as a myeloid downregulatory signal.Immune Checkpoint Immunotherapy Cancer Immunotherapy Targeted Therapy
- Technical data
- Alternative to gene target
- [ "CD200 receptor 1", "CD200R1 and IDBG-50029 and ENSG00000163606 and 131450", "protein binding", "Extracellular" ]
- Gene targetCD200R1 / OX-2R Protein His tag 100µg
- Identity:HGNC:24235
- Gene:CD200R1
- Long gene name:CD200 receptor 1
- Synonyms gene name:MOX2 receptor
- Synonyms:OX2RHCRTR2CD200R
- Discovery year:2004-07-12
- Entrez gene record:131450
- Pubmed identification:10981966, 11133863
- RefSeq identity:NM_138806
- Classification:C2-set domain containing
- VEGA ID:OTTHUMG00000159298
- Identity:HGNC:18158
- Gene:VCX2
- Long gene name:variable charge X-linked 2
- Synonyms:VCX-2rVCX-2R
- Discovery year:2004-04-16
- Entrez gene record:51480
- Pubmed identification:10607842
- RefSeq identity:NM_016378
- Classification:Variable charge X/Y family
- VEGA ID:OTTHUMG00000021105
- Identity:HGNC:4847
- Gene:HCRT
- Long gene name:hypocretin neuropeptide precursor
- Synonyms gene name:hypocretin (orexin) neuropeptide precursor
- Synonyms:PPOXOX
- Discovery year:1998-04-21
- Entrez gene record:3060
- Pubmed identification:9419374, 9491897
- RefSeq identity:NM_001524
- Classification:Neuropeptides
- VEGA ID:OTTHUMG00000180107
- Identity:HGNC:4849
- Gene:HCRTR2
- Long gene name:hypocretin receptor 2
- Synonyms gene name:hypocretin (orexin) receptor 2
- Synonyms:OX2ROXR2ORXR2
- Discovery year:1998-04-21
- Entrez gene record:3062
- Pubmed identification:9491897
- Classification:Hypocretin receptors
- VEGA ID:OTTHUMG00000016150
- Identity:HGNC:7203
- Gene:CD200
- Long gene name:CD200 molecule
- Synonyms gene name:antigen identified by monoclonal antibody MRC OX-2, CD200 antigen
- Synonyms:MRC, OX-2
- Discovery year:2001-06-22
- Entrez gene record:4345
- Classification:CD molecules, Immunoglobulin like domain containing
- VEGA ID:OTTHUMG00000159248
- Identity:HGNC:11934
- Gene:TNFSF4
- Long gene name:TNF superfamily member 4
- Synonyms gene name:tax-transcriptionally activated glycoprotein 1, 34kD, tumor necrosis factor (ligand) superfamily, member 4
- Synonyms:OX-40L, gp34CD252
- Discovery year:1993-12-15
- Entrez gene record:7292
- Pubmed identification:1996093, 8076595
- Classification:Tumor necrosis factor superfamily, CD molecules
- VEGA ID:OTTHUMG00000034838
- Gene symbolCD200R1, VCX2, HCRT, HCRTR2, CD200, TNFSF4
- Hostmouse
- Short nameRecombinant Mouse CD200R1 / OX-2R Protein (His tag) 100µg
- LabelHis
- label filter
- His
- technique filter
- Recombinant
- Mouse
- TechniqueRecombinant, Mouse, mouses, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. Elabscience advises they will be reconstituted in a buffer soluion or culture medium for cell culture. Tags
- Alternative techniquerec, murine