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Recombinant Human CD200R1L / CD200R2 / CD200RLa Protein (His tag) 100µg

  • Catalog number
    PKSH031061-100µg
  • Product name
    Recombinant Human CD200R1L / CD200R2 / CD200RLa Protein (His tag) 100µg
  • Size
    100µg
  • Synonym
    CD200R2;CD200RLa
  • Activity
    NA
  • Sequence
    Met1-Leu239
  • Fusion tag
    C-His
  • Accession
    AAT00538.1
  • Expressed Host
    HEK293 Cells
  • Shipping
    In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature.Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.
  • Purity
    ＞95 % as determined by SDS-PAGE
  • Endotoxin
    ＜1.0 EU per µg as determined by the LAL method
  • Stability and Storage
    Samples are stable for up to twelve months from date of receipt at -70℃.Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
  • Mol Mass
    25.2 kDa
  • AP Mol Mass
    45-60 kDa
  • Formulation
    Lyophilized from sterile PBS, pH 7.4
  • Reconstitution
    Please refer to it for detailed information.
  • Background
    Cell surface glycoprotein CD200 receptor 2, also known as Cell surface glycoprotein CD200 receptor 1-like, Cell surface glycoprotein OX2 receptor 2, CD200 receptor-like 2, CD200Rla, CD200R1L and CD200R2, is a single-pass type I  membrane protein which belongs to the CD200R family. CD200R1L / CD200R2. It contains one Ig-like C2-type (immunoglobulin-like) domain and one Ig-like V-type (immunoglobulin-like) domain. CD200 is a transmembrane protein delivering immunoregulatory signals after engagement of CD200R. A family of CD200Rs exist ( CD200R1, CD200R2, CD200R3, CD200R4 ) with different tissue expression and functional activity. In the presence of anti-CD200R2 / CD200R3 monoclonal antibodies (mAbs), bone-marrow cells cultured in the presence of (interleukin [IL]-4+granulocyte-macrophage colony-stimulating factor) differentiate into dendritic cells (DCs), which induce CD4+CD25+ Treg. Interaction between the relatively ubiquitously expressed molecule CD200 and one of its receptors, CD200R1, resulted in direct suppression of alloreactivity, engagement of alternate receptors led instead to altered differentiation of dendritic cells (DCs) from marrow precursors, which could in turn foster development of Foxp3(+) regulatory T cells. Unlike anti-CD200R1, anti-CD200R2 both promotes development of DCs with capacity to induce Treg and directly augments thymocyte production of Treg.
  • Product URL
    Product_URL
  • PDF URL
    PDF_URL
  • Alternative to gene target
    • [ "CD200 receptor 1-like", "CD200R1L and IDBG-50020 and ENSG00000206531 and 344807", "protein binding", "Plasma membranes" ]
  • Gene target
    CD200R1L / CD200R2 / CD200RLa Protein His tag 100µg
    • Gene info
    Gene info
  • Gene symbol
    CD200R1L, CD200R1L-AS1
  • Short name
    Recombinant CD200R1L / CD200R2 / CD200RLa Protein (His tag) 100µg
  • Label
    His
  • label filter
    • His
  • technique filter
    • Recombinant
  • Technique
    Recombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. Elabscience advises they will be reconstituted in a buffer soluion or culture medium for cell culture. Tags
  • Alternative technique
    rec