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Recombinant Human Bone Marrow Stromal Antigen 2 Protein

  • Catalog number
    PKSH030643-10µg
  • Product name
    Recombinant Human Bone Marrow Stromal Antigen 2 Protein
  • Size
    10µg
  • Synonym
    Bone Marrow Stromal Antigen 2; BST-2; HM1.24 Antigen; Tetherin; CD317; BST2
  • Activity
    NA
  • Sequence
    Asn49-Ser161
  • Fusion tag
    C-6His
  • Accession
    Q10589
  • Expressed Host
    Human cells
  • Shipping
    The product is shipped at ambient temperature.Upon receipt, store it immediately at the temperature listed below.
  • Purity
    ＞95% as determined by reducing SDS-PAGE.
  • Endotoxin
    ＜1.0 EU per µg as determined by LAL test.
  • Stability and Storage
    Lyophilized protein should be stored at < -20℃, though stable at room temperature for 3 weeks.Reconstituted protein solution can be stored at 4-7℃ for 2-7 days.Aliquots of reconstituted samples are stable at < -20℃ for 3 months
  • Mol Mass
    13.7 kDa
  • AP Mol Mass
    23 kDa
  • Formulation
    Lyophilized from a 0.2 μm filtered solution of 20mM PB,150mM NaCl,pH7.4.
  • Background
    Bone Marrow Stromal Antigen 2 (BST2) is a single-pass type II membrane protein that belongs to the tetherin family. BST2 is predominantly expressed in the liver, lung, heart and placenta. BST2 is involved in the sorting of secreted proteins. BST2 is a human cellular protein which inhibits retrovirus infection by preventing the diffusion of virus particles after budding from infected cells. BST2 is initially discovered as an inhibitor to HIV-1 infection in the absence of Vpu, it has also been shown to inhibit the release of other viruses such as retroviruses, filoviruses, arenaviruses, and herpes viruses. BST2 may play a role in B-cell activation in rheumatoid arthritis.
  • Technical data
    Technical_data
  • Gene target
    Bone Marrow Stromal 2 Protein
  • Short name
    Recombinant Bone Marrow Stromal Antigen 2 Protein
  • technique filter
    • Recombinant
    • antigen
  • Technique
    Recombinant, antigen, antigenes, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. Elabscience advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
  • Alternative technique
    rec, antigenes
  • Tissue
    bone, marrow
  • tissue filter
    • bone
    • marrow