- Catalog numberPKSH031071-100µg
- Product nameRecombinant Human ATF2 Protein (His & GST tag) 100µg
- Size100µg
- PriceAsk For Price
- SynonymCRE-BP1;CREB-2;CREB2;HB16;TREB7
- ActivityNA
- SequenceMet 1-Ser 505
- Fusion tagN-His & GST
- AccessionP15336-1
- Expressed HostBaculovirus-Insect Cells
- ShippingIn general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature.Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.
- Purity>90 % as determined by SDS-PAGE
- Endotoxin<1.0 EU per µg as determined by the LAL method
- Stability and StorageSamples are stable for up to twelve months from date of receipt at -70℃.Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
- Mol Mass82.4 kDa
- AP Mol Mass85 kDa
- FormulationLyophilized from sterile 20mM Tris, 500mM NaCl, pH 8.0, 10% gly
- ReconstitutionPlease refer to it for detailed information.
- BackgroundActivating transcription factor 2, also known as ATF2, is a member of the leucine zipper family of DNA-binding proteins that binds to the cAMP response element. Its activity is enhanced after phosphorylation by stress-activated protein kinases such as c-Jun N-terminal kinase and p38. ATF2 has been found to be a target of the JNK signal transduction pathway and mediate adenovirus E1A-inducible transcriptional activation. ATF2 is also been reported playing roles in TGF-β signaling pathway. It has been shown that the transcription factor ATF2 is bound by a hetero-oligomer of Smad3 and Smad4 upon TGF-β stimulation. Studies indicate that ATF-2 plays a central role in TGF-β signaling by acting as a common nuclear target of both Smad and TAK1 pathways.
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- Gene targetATF2 Protein His GST tag 100µg
- Identity:HGNC:784
- Gene:ATF2
- Long gene name:activating transcription factor 2
- Synonyms gene name:cAMP responsive element binding protein 2
- Synonyms:TREB7CRE-BP1HB16
- Discovery year:1991-08-01
- Entrez gene record:1386
- Pubmed identification:1833307, 1838349
- RefSeq identity:NM_001880
- Classification:Basic leucine zipper proteins, MicroRNA protein coding host genes
- VEGA ID:OTTHUMG00000132424
- Gene symbolMGST3, GDNF, ATF2
- Short nameRecombinant ATF2 Protein (His & GST tag) 100µg
- LabelHis
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- His
- technique filter
- Recombinant
- TechniqueRecombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. Elabscience advises they will be reconstituted in a buffer soluion or culture medium for cell culture. Tags
- Alternative techniquerec