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PARK7 Antibody

  • Catalog number
    bs-5708R-Cy3
  • Product name
    SUV39H1 Antibody, Cy3 Conjugated
  • Size
    0.1ml
  • Short name
    Anti-SUV39H1
  • Long name
    SUV39H1 Polyclonal Antibody, Cy3 Conjugated
  • Category
    Conjugated Primary Antibodies
  • Conjugation
    Cy3
  • Host Organism
    Rabbit (Oryctolagus cuniculus)
  • Target Antigen
    SUV39H1
  • Specificity
    This is a highly specific antibody against SUV39H1.
  • Modification
    Unmodified
  • Modification site
    None
  • Clonality
    Polyclonal
  • Clone
    Polyclonal antibody
  • Isotype
    Immunoglobulin G (IgG)
  • Concentration
    1ug per 1ul
  • Subcellular location
    Nucleus
  • Source
    KLH conjugated synthetic peptide derived from human Histone-lysine N-methyltransferase SUV39H1
  • Gene ID number
    6839
  • Tested applications
    IF(IHC-P)
  • Recommended dilutions
    IF(IHC-P)(1:50-200)
  • Crossreactivity
    Human, Mouse, Rat
  • Crossreactive species details
    Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
  • Antigen background
    SUV39H1 is targeted to histone H3 via its interaction with RB1 and is involved in many processes, such as repression of MYOD1-stimulated differentiation, regulation of the control switch for exiting the cell cycle and entering differentiation, repression by the PML-RARA fusion protein, BMP-induced repression, repression of switch recombination to IgA and regulation of telomere length. Component of the eNoSC (energy-dependent nucleolar silencing) complex, a complex that mediates silencing of rDNA in response to intracellular energy status and acts by recruiting histone-modifying enzymes. The eNoSC complex is able to sense the energy status of cell: upon glucose starvation, elevation of NAD(+)/NADP(+) ratio activates SIRT1, leading to histone H3 deacetylation followed by dimethylation of H3 at 'Lys-9' (H3K9me2) by SUV39H1 and the formation of silent chromatin in the rDNA locus.
  • Purification method
    This antibody was purified via Protein A.
  • Storage conditions
    Keep the antibody in an aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store refrigerated at 2 to 8 degrees Celcius for up to 1 year.
  • Excitation Emission
    512,550nm/570,615nm
  • Synonyms
    H3 K9 HMTase; H3 K9 HMTase1; H3-K9-HMTase 1; Histone H3 K9 methylation; Histone H3 Lys 9 methylation; Histone H3-K9 methyltransferase 1; Histone H3-K9 methyltransferase1; Histone lysine N methyltransferase H3 lysine 9 specic 1; Histone lysine N methyltransferase, H3 lysine 9 specic 1; Histone-lysine N-methyltransferase SUV39H1; KMT1 A; Lysine N methyltransferase 1A; Lysine N-methyltransferase 1A; MG44; mIS6; Position-effect variegation 3-9 homolog; Suvar3 9 homolog 1; Suvar3-9 homolog 1; Suppressor of variegation 3 9 homolog 1 Drosophila; Suppressor of variegation 3-9 homolog 1; SUV39 H1; SUV39H; SUV39H1; SUV91_HUMAN.
  • Gene target
    SUV39H1 Conjugated
    • Gene info
    Locus Specific Databases:Global Variome shared LOVD
  • Gene symbol
    SUV39H1
  • isotype filter
    • Immunoglobulin G IgG
  • Label
    Cy3
  • label filter
    • Cy3
  • technique filter
    • Antibody
  • Technique
    Antibody, antibodies against human proteins, antibodies for, antibody Conjugates
  • Alternative technique
    antibodies