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Rabbit Anti Human USP20 Antibody-Biotin

  • Catalog number
    CSB-PA896876LD01HU_50ug
  • Product name
    Rabbit Anti Human USP20 Antibody-Biotin
  • Size
    50ug
  • Long name
    Rabbit Antibody against Human USP20, Biotin
  • Short name
    Anti-USP20
  • Synonym name
    USP20 Human Antibody
  • Host
    Rabbit, Rabbits
  • Species reactivity
    Human
  • Tested applications recommended dilutions
    ELISA
  • Conjugation
    Biotin
  • Antibody isotype
    IgG
  • UniProt ID
    Q9Y2K6
  • Format
    Liquid, diluted in buffer
  • Buffer composition
    Preservative: 0.03% Proclin 300, Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • Purity
    >95%
  • Purification method
    Protein G purified
  • Antibody category
    Polyclonal Antibodies
  • Immunogen type
    Recombinant Human Ubiquitin carboxyl-terminal hydrolase 20 protein (258-417AA)
  • Immunogen species
    Human
  • Alias
    Ubiquitin carboxyl-terminal hydrolase 20,Deubiquitinating enzyme 20,Ubiquitin thioesterase 20,Ubiquitin-specific-processing protease 20,VHL-interacting deubiquitinating enzyme 2,hVDU2,USP20,KIAA1003,LSFR3A,VDU2
  • Background
    Deubiquitinating enzyme involved in beta-2 adrenergic receptor (ADRB2) recycling. Acts as a regulator of G-protein coupled receptor (GPCR) signaling by mediating the deubiquitination beta-2 adrenergic receptor (ADRB2). Plays a central role in ADRB2 recycling and resensitization after prolonged agonist stimulation by constitutively binding ADRB2, mediating deubiquitination of ADRB2 and inhibiting lysosomal trafficking of ADRB2. Upon dissociation, it is probably transferred to the translocated beta-arrestins, possibly leading to beta-arrestins deubiquitination and disengagement from ADRB2. This suggests the existence of a dynamic exchange between the ADRB2 and beta-arrestins. Deubiquitinates DIO2, thereby regulating thyroid hormone regulation. Deubiquitinates HIF1A, leading to stabilize HIF1A and enhance HIF1A-mediated activity. Mediates deubiquitination of both 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains.
  • Clonality
    Polyclonal antibody
  • Shipping and storage
    USP20 Antibody is shipped on ice packs and upon receipt should be stored at -20 or -80 degrees Celsius. We recommend that you prepare the working aliquots in advance so that freez-thaw cycles are avoided. Do not expose the antibodies to drirect bright light, especially the labeled ones as most conjugates are light sensitive.
  • Short name of the antigen
    Ubiquitin carboxyl-terminal hydrolase 20
  • Alternative to gene target
    • [ "ubiquitin specific peptidase 20", "hVDU2 and LSFR3A and VDU2", "USP20 and IDBG-89323 and ENSG00000136878 and 10868", "ubiquitinyl hydrolase activity", "Cytoplasm", "Usp20 and IDBG-157301 and ENSMUSG00000026854 and 74270", "USP20 and IDBG-639759 and ENSBTAG00000020311 and 505839" ]
  • Gene target
    USP20 -
    • Gene info
    Locus Specific Databases:LRG_711
  • Gene symbol
    USP20
  • Label
    Biotin
  • label filter
    • Biotin
  • technique filter
    • anti human
    • Antibody
    • Rabbit
    • anti
  • Technique
    anti human, Antibody, Rabbit, anti, antibody to, anti human antibodies, antibodies against human proteins, antibodies for
  • Alternative technique
    antibodies, rabbit-anti