- Catalog numberCSB-PA891791ESR1HU_100ul
- Product nameRabbit Anti Human TNFSF18 Antibody-Non-conjugated
- Size100ul
- PriceAsk For Price
- Long nameRabbit Antibody against Human TNFSF18, Non-conjugated
- Short nameAnti-TNFSF18
- Synonym nameTNFSF18 Human Antibody
- HostRabbit, Rabbits
- Species reactivityHuman
- Tested applications recommended dilutionsELISA,IHC;Recommended dilution:IHC:1:20-1:200
- ConjugationNon-conjugated
- Antibody isotypeIgG
- UniProt IDQ9UNG2
- FormatLiquid, diluted in buffer
- Buffer compositionPBS with 0.02% sodium azide, 50% glycerol, pH7.3.
- Purity>95%
- Purification methodAntigen Affinity Purified Antibodies
- Antibody categoryPolyclonal Antibodies
- Immunogen typeRecombinant human Tumor necrosis factor ligand superfamily member 18 protein (72-199AA)
- Immunogen speciesHuman
- AliasActivation-inducible TNF-related ligand,AITRL,Glucocorticoid-induced TNF-related ligand,hGITRL,TNFSF18,AITRL, GITRL, TL6,UNQ149/PRO175
- BackgroundCytokine that binds to TNFRSF18/AITR/GITR. Regulates T-cell responses. Can function as costimulator and lower the threshold for T-cell activation and T-cell proliferation. Important for interactions between activated T-lymphocytes and endothelial cells. Mediates activation of NF-kappa-B. Triggers increased phosphorylation of STAT1 and up-regulates expression of VCAM1 and ICAM1 (PubMed:23892569). Promotes leukocyte adhesion to endothelial cells (PubMed:23892569). Regulates migration of monocytes from the splenic reservoir to sites of inflammation.
- ClonalityPolyclonal antibody
- Shipping and storageTNFSF18 Antibody is shipped on ice packs and upon receipt should be stored at -20 or -80 degrees Celsius. We recommend that you prepare the working aliquots in advance so that freez-thaw cycles are avoided. Do not expose the antibodies to drirect bright light, especially the labeled ones as most conjugates are light sensitive.
- Alternative to gene target
- [ "tumor necrosis factor (ligand) superfamily, member 18", "AITRL and GITRL and hGITRL and TL6", "TNFSF18 and IDBG-104861 and ENSG00000120337 and 8995", "tumor necrosis factor receptor superfamily binding", "Extracellular", "Tnfsf18 and IDBG-201543 and ENSMUSG00000066755 and 240873", "LOC768081 and IDBG-632315 and ENSBTAG00000047412 and 768081" ]
- Gene targetTNFSF18 Non-conjugated
- Identity:HGNC:11932
- Gene:TNFSF18
- Long gene name:TNF superfamily member 18
- Synonyms gene name:tumor necrosis factor (ligand) superfamily, member 18
- Synonyms:AITRLTL6hGITRL
- Discovery year:1999-01-15
- Entrez gene record:8995
- Pubmed identification:10037686, 10074428
- RefSeq identity:NM_005092
- Classification:Tumor necrosis factor superfamily
- VEGA ID:OTTHUMG00000034835
- Gene symbolTNFSF18
- technique filter
- anti human
- Antibody
- Rabbit
- anti
- Techniqueanti human, Antibody, Rabbit, anti, antibody to, anti human antibodies, antibodies against human proteins, antibodies for, antibody Conjugates
- Alternative techniqueantibodies, rabbit-anti