• Catalog number
    CSB-PA624010HD01HU_100ug
  • Product name
    Rabbit Anti Human SART3 Antibody-Biotin
  • Size
    100ug
  • Long name
    Rabbit Antibody against Human SART3, Biotin
  • Short name
    Anti-SART3
  • Synonym name
    SART3 Human Antibody
  • Host
    Rabbit, Rabbits
  • Species reactivity
    Human
  • Tested applications recommended dilutions
    ELISA
  • Conjugation
    Biotin
  • Antibody isotype
    IgG
  • UniProt ID
    Q15020
  • Format
    Liquid, diluted in buffer
  • Buffer composition
    Preservative: 0.03% Proclin 300, Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • Purity
    >95%
  • Purification method
    Protein G purified
  • Antibody category
    Polyclonal Antibodies
  • Immunogen type
    Recombinant human Squamous cell carcinoma antigen recognized by T-cells 3 protein (600-900AA)
  • Immunogen species
    Human
  • Alias
    Squamous cell carcinoma antigen recognized by T-cells 3Curated,SART-3Imported,SART3,Tat-interacting protein of 110 kDa1
  • Background
    U6 snRNP-binding protein that functions as a recycling factor of the splicing machinery. Promotes the initial reassembly of U4 and U6 snRNPs following their ejection from the spliceosome during its maturation (PubMed:12032085). Also binds U6atac snRNPs and may function as a recycling factor for U4atac/U6atac spliceosomal snRNP, an initial step in the assembly of U12-type spliceosomal complex. The U12-type spliceosomal complex plays a role in the splicing of introns with non-canonical splice sites (PubMed:14749385). May also function as a substrate-targeting factor for deubiquitinases like USP4 and USP15. Recruits USP4 to ubiquitinated PRPF3 within the U4/U5/U6 tri-snRNP complex, promoting PRPF3 deubiquitination and thereby regulating the spliceosome U4/U5/U6 tri-snRNP spliceosomal complex disassembly (PubMed:20595234). May also recruit the deubiquitinase USP15 to histone H2B and mediate histone deubiquitination, thereby regulating gene expression and/or DNA repair (PubMed:24526689). May play a role in hematopoiesis probably through transcription regulation of specific genes including MYC (By similarity).
  • Clonality
    Polyclonal antibody
  • Shipping and storage
    SART3 Antibody is shipped on ice packs and upon receipt should be stored at -20 or -80 degrees Celsius. We recommend that you prepare the working aliquots in advance so that freez-thaw cycles are avoided. Do not expose the antibodies to drirect bright light, especially the labeled ones as most conjugates are light sensitive.
  • Alternative to gene target
    • [ "squamous cell carcinoma antigen recognized by T cells 3", "DSAP1 and P100 and p110 and p110(nrb) and RP11-13G14 and TIP110", "SART3 and IDBG-55333 and ENSG00000075856 and 9733", "poly(A) RNA binding", "nuclei", "Sart3 and IDBG-191800 and ENSMUSG00000018974 and 53890", "BT.22766 and IDBG-635596 and ENSBTAG00000031846 and 505922" ]
  • Gene target
    SART3 -
  • Gene info
  • Gene symbol
    SART3
  • Label
    Biotin
  • label filter
    • Biotin
  • technique filter
    • anti human
    • Antibody
    • Rabbit
    • anti
  • Technique
    anti human, Antibody, Rabbit, anti, antibody to, anti human antibodies, antibodies against human proteins, antibodies for
  • Alternative technique
    antibodies, rabbit-anti