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Rabbit Anti Human RNF40 Antibody-FITC

  • Catalog number
    CSB-PA019890LC01HU_100ug
  • Product name
    Rabbit Anti Human RNF40 Antibody-FITC
  • Size
    100ug
  • Long name
    Rabbit Antibody against Human RNF40, FITC
  • Short name
    Anti-RNF40
  • Synonym name
    RNF40 Human Antibody
  • Host
    Rabbit, Rabbits
  • Species reactivity
    Human
  • Tested applications recommended dilutions
    ELISA
  • Conjugation
    FITC
  • Antibody isotype
    IgG
  • UniProt ID
    O75150
  • Format
    Liquid, diluted in buffer
  • Buffer composition
    Preservative: 0.03% Proclin 300, Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • Purity
    >95%
  • Purification method
    Protein G purified
  • Antibody category
    Polyclonal Antibodies
  • Immunogen type
    Recombinant Human E3 ubiquitin-protein ligase BRE1B protein (471-724AA)
  • Immunogen species
    Human
  • Alias
    E3 ubiquitin-protein ligase BRE1B,BRE1-B,95 kDa retinoblastoma-associated protein,RBP95,RING finger protein 40,RNF40,BRE1B,KIAA0661
  • Background
    Component of the RNF20/40 E3 ubiquitin-protein ligase complex that mediates monoubiquitination of 'Lys-120' of histone H2B (H2BK120ub1). H2BK120ub1 gives a specific tag for epigenetic transcriptional activation and is also prerequisite for histone H3 'Lys-4' and 'Lys-79' methylation (H3K4me and H3K79me, respectively). It thereby plays a central role in histone code and gene regulation. The RNF20/40 complex forms a H2B ubiquitin ligase complex in cooperation with the E2 enzyme UBE2A or UBE2B; reports about the cooperation with UBE2E1/UBCH are contradictory. Required for transcriptional activation of Hox genes.
  • Clonality
    Polyclonal antibody
  • Shipping and storage
    RNF40 Antibody is shipped on ice packs and upon receipt should be stored at -20 or -80 degrees Celsius. We recommend that you prepare the working aliquots in advance so that freez-thaw cycles are avoided. Do not expose the antibodies to drirect bright light, especially the labeled ones as most conjugates are light sensitive.
  • Short name of the antigen
    E3 ubiquitin-protein ligase BRE1B
  • Gene target
    RNF40 -
    • Gene info
  • Gene symbol
    RNF40
  • Label
    FITC
  • label filter
    • FITC
  • technique filter
    • anti human
    • Antibody
    • Rabbit
    • anti
    • FITC
  • Technique
    anti human, Antibody, Rabbit, anti, FITC, antibody to, anti human antibodies, antibodies against human proteins, antibodies for, Fluorescein
  • Alternative technique
    antibodies, rabbit-anti, fluorescine