- Catalog numberCSB-PA620876LD01HU_100ug
- Product nameRabbit Anti Human PPP2R4 Antibody-Biotin
- Size100ug
- PriceAsk For Price
- Long nameRabbit Antibody against Human PPP2R4, Biotin
- Short nameAnti-PPP2R4
- Synonym namePPP2R4 Human Antibody
- HostRabbit, Rabbits
- Species reactivityHuman
- Tested applications recommended dilutionsELISA
- ConjugationBiotin
- Antibody isotypeIgG
- UniProt IDQ15257
- FormatLiquid, diluted in buffer
- Buffer compositionPreservative: 0.03% Proclin 300, Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
- Purity>95%
- Purification methodProtein G purified
- Antibody categoryPolyclonal Antibodies
- Immunogen typeRecombinant human Serine/threonine-protein phosphatase 2A activator protein (1-250AA)
- Immunogen speciesHuman
- AliasSerine/threonine-protein phosphatase 2A activator (EC:5.2.1.8),PPP2R4,PTPA,PP2A,subunit B',PR53 isoform,Phosphotyrosyl phosphatase activator,PTPA,Serine/threonine-protein phosphatase 2A regulatory subunit 4,Serine/threonine-protein phosphatase 2A regulatory subunit B'
- BackgroundPPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. Acts as a regulatory subunit for serine/threonine-protein phosphatase 2A (PP2A) modulating its activity or substrate specificity, probably by inducing a conformational change in the catalytic subunit, a proposed direct target of the PPIase. Can reactivate inactive phosphatase PP2A-phosphatase methylesterase complexes (PP2A(i)) in presence of ATP and Mg(2+) (By similarity). Reversibly stimulates the variable phosphotyrosyl phosphatase activity of PP2A core heterodimer PP2A(D) in presence of ATP and Mg(2+) (in vitro). The phosphotyrosyl phosphatase activity is dependent of an ATPase activity of the PP2A(D):PPP2R4 complex. Is involved in apoptosis; the function appears to be independent from PP2A.
- ClonalityPolyclonal antibody
- Shipping and storagePPP2R4 Antibody is shipped on ice packs and upon receipt should be stored at -20 or -80 degrees Celsius. We recommend that you prepare the working aliquots in advance so that freez-thaw cycles are avoided. Do not expose the antibodies to drirect bright light, especially the labeled ones as most conjugates are light sensitive.
- Alternative to gene target
- [ "protein phosphatase 2A activator, regulatory subunit 4", "PP2A and PR53 and PTPA", "PPP2R4 and IDBG-89032 and ENSG00000119383 and 5524", "protein phosphatase 2A binding", "nuclei", "Ppp2r4 and IDBG-156714 and ENSMUSG00000039515 and 110854", "PPP2R4 and IDBG-639691 and ENSBTAG00000001933 and 514460" ]
- Gene targetPPP2R4 -
- Identity:HGNC:9308
- Gene:PTPA
- Long gene name:protein phosphatase 2 phosphatase activator
- Synonyms gene name:protein phosphatase 2A, regulatory subunit B' (PR 53), protein phosphatase 2A activator, regulatory subunit 4, protein phosphatase 2 regulatory subunit 4
- Synonyms:PR53,
- Discovery year:1994-06-09
- Entrez gene record:5524
- Pubmed identification:8530035, 16380387
- RefSeq identity:NM_021131
- Classification:Protein phosphatase 2 modulatory subunits, Cyclophilin peptidylprolyl isomerases
- VEGA ID:OTTHUMG00000020774
- Identity:HGNC:51184
- Gene:LINC01503
- Long gene name:long intergenic non-protein coding RNA 1503
- Synonyms:lnc-PPP2R4-5RP11-65J3.1
- Discovery year:2014-08-01
- Entrez gene record:100506119
- Pubmed identification:25045670, 29436261
- RefSeq identity:NR_120685
- Classification:Long intergenic non-protein coding RNAs
- VEGA ID:OTTHUMG00000020778
- Gene symbolPTPA, LINC01503
- LabelBiotin
- label filter
- Biotin
- technique filter
- anti human
- Antibody
- Rabbit
- anti
- Techniqueanti human, Antibody, Rabbit, anti, antibody to, anti human antibodies, antibodies against human proteins, antibodies for
- Alternative techniqueantibodies, rabbit-anti