- Catalog numberCSB-PA010166LA01HU_100ug
- Product nameRabbit Anti Human HCFC1 Antibody-Non-conjugated
- Size100ug
- PriceAsk For Price
- Long nameRabbit Antibody against Human HCFC1, Non-conjugated
- Short nameAnti-HCFC1
- Synonym nameHCFC1 Human Antibody
- HostRabbit, Rabbits
- Species reactivityHuman
- Tested applications recommended dilutionsELISA,IHC,IF;Recommended dilution:IHC:1:20-1:200,IF:1:50-1:200
- ConjugationNon-conjugated
- Antibody isotypeIgG
- UniProt IDP51610
- FormatLiquid, diluted in buffer
- Buffer compositionPreservative: 0.03% Proclin 300, Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
- Purity>95%
- Purification methodProtein G purified
- Antibody categoryPolyclonal Antibodies
- Immunogen typeRecombinant human Host cell factor 1 protein (201-428AA)
- Immunogen speciesHuman
- AliasHost cell factor 1HCFHCF-1,C1 factor,CFF,VCAF,VP16 accessory protein,HCF N-terminal chain 1,HCF N-termi,HCFC1,HCF1,HFC1
- BackgroundInvolved in control of the cell cycle. Also antagonizes transactivation by ZBTB17 and GABP2; represses ZBTB17 activation of the p15(INK4b) promoter and inhibits its ability to recruit p300. Coactivator for EGR2 and GABP2. Tethers the chromatin modifying Set1/Ash2 histone H3 'Lys-4' methyltransferase (H3K4me) and Sin3 histone deacetylase (HDAC) complexes (involved in the activation and repression of transcription, respectively) together. Component of a THAP1/THAP3-HCFC1-OGT complex that is required for the regulation of the transcriptional activity of RRM1. As part of the NSL complex it may be involved in acetylation of nucleosomal histone H4 on several lysine residues. In case of human herpes simplex virus (HSV) infection, HCFC1 forms a multiprotein-DNA complex with the viral transactivator protein VP16 and POU2F1 thereby enabling the transcription of the viral immediate early genes.
- ClonalityPolyclonal antibody
- Shipping and storageHCFC1 Antibody is shipped on ice packs and upon receipt should be stored at -20 or -80 degrees Celsius. We recommend that you prepare the working aliquots in advance so that freez-thaw cycles are avoided. Do not expose the antibodies to drirect bright light, especially the labeled ones as most conjugates are light sensitive.
- Short name of the antigenHost cell factor 1
- Alternative to gene target
- [ "host cell factor C1 (VP16-accessory protein)", "CFF and HCF-1 and HCF1 and HFC1 and MRX3 and PPP1R89 and VCAF", "HCFC1 and IDBG-90667 and ENSG00000172534 and 3054", "histone acetyltransferase activity (H4-K16 specific)", "nuclei", "Hcfc1 and IDBG-154574 and ENSMUSG00000031386 and 102642211,15161", "HCFC1 and IDBG-632542 and ENSBTAG00000011904 and 512908" ]
- Gene targetHCFC1 Non-conjugated
- Identity:HGNC:40273
- Gene:HCFC1-AS1
- Long gene name:HCFC1 antisense RNA 1
- Synonyms gene name:HCFC1 antisense RNA 1 (non-protein coding)
- Discovery year:2011-07-29
- Classification:Antisense RNAs
- VEGA ID:OTTHUMG00000024223
- Identity:HGNC:4839
- Gene:HCFC1
- Long gene name:host cell factor C1
- Synonyms gene name:mental retardation, X-linked 3, host cell factor C1 (VP16-accessory protein)
- Synonyms:HCF-1, HCF1CFFVCAFMGC70925PPP1R89
- Discovery year:1994-10-14
- Entrez gene record:3054
- Pubmed identification:8392914, 23000143
- RefSeq identity:NM_005334
- Classification:Protein phosphatase 1 regulatory subunits, ATAC complex, NSL histone acetyltransferase complex
- VEGA ID:OTTHUMG00000024222
- Gene symbolHCFC1-AS1, HCFC1
- technique filter
- anti human
- Antibody
- Rabbit
- anti
- Techniqueanti human, Antibody, Rabbit, anti, antibody to, anti human antibodies, antibodies against human proteins, antibodies for, antibody Conjugates
- Alternative techniqueantibodies, rabbit-anti
Gene info
Gene info
Locus Specific Databases:Global Variome shared LOVD