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Rabbit Anti Human DSCAM Antibody-Biotin

  • Catalog number
    CSB-PA007192LD01HU_100ug
  • Product name
    Rabbit Anti Human DSCAM Antibody-Biotin
  • Size
    100ug
  • Long name
    Rabbit Antibody against Human DSCAM, Biotin
  • Short name
    Anti-DSCAM
  • Synonym name
    DSCAM Human Antibody
  • Host
    Rabbit, Rabbits
  • Species reactivity
    Human
  • Tested applications recommended dilutions
    ELISA
  • Conjugation
    Biotin
  • Antibody isotype
    IgG
  • UniProt ID
    O60469
  • Format
    Liquid, diluted in buffer
  • Buffer composition
    Preservative: 0.03% Proclin 300, Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • Purity
    >95%
  • Purification method
    Protein G purified
  • Antibody category
    Polyclonal Antibodies
  • Immunogen type
    Recombinant Human Down syndrome cell adhesion molecule protein (1711-1867AA)
  • Immunogen species
    Human
  • Alias
    Down syndrome cell adhesion molecule, CHD2, DSCAM
  • Background
    Cell adhesion molecule that plays a role in neuronal self-avoidance. Promotes repulsion between specific neuronal processes of either the same cell or the same subtype of cells. Mediates within retinal amacrine and ganglion cell subtypes both isoneuronal self-avoidance for creating an orderly dendritic arborization and heteroneuronal self-avoidance to maintain the mosaic spacing between amacrine and ganglion cell bodies (PubMed:10925149). Receptor for netrin required for axon guidance independently of and in collaboration with the receptor DCC. In spinal chord development plays a role in guiding commissural axons projection and pathfinding across the ventral midline to reach the floor plate upon ligand binding (PubMed:18585357, PubMed:19196994). Enhances netrin-induced phosphorylation of PAK1 and FYN (PubMed:15169762). Mediates intracellular signaling by stimulating the activation of MAPK8 and MAP kinase p38 (PubMed:18585357, PubMed:19196994). Adhesion molecule that promotes lamina-specific synaptic connections in the retina: expressed in specific subsets of interneurons and retinal ganglion cells (RGCs) and promotes synaptic connectivity via homophilic interactions (By similarity).
  • Clonality
    Polyclonal antibody
  • Shipping and storage
    DSCAM Antibody is shipped on ice packs and upon receipt should be stored at -20 or -80 degrees Celsius. We recommend that you prepare the working aliquots in advance so that freez-thaw cycles are avoided. Do not expose the antibodies to drirect bright light, especially the labeled ones as most conjugates are light sensitive.
  • Short name of the antigen
    Down syndrome cell adhesion molecule
  • Alternative to gene target
    • [ "Down syndrome cell adhesion molecule", "CHD2 and CHD2-42 and CHD2-52", "DSCAM and IDBG-3815 and ENSG00000171587 and 1826", "protein binding", "Extracellular", "Dscam and IDBG-180173 and ENSMUSG00000050272 and 13508", "DSCAM and IDBG-639205 and ENSBTAG00000004754 and 100337016,101908463" ]
  • Gene target
    DSCAM -
    • Gene info
    Gene info
    Gene info
  • Gene symbol
    DSCAM-IT1, DSCAM-AS1, DSCAM
  • Label
    Biotin
  • label filter
    • Biotin
  • technique filter
    • anti human
    • Antibody
    • Rabbit
    • anti
  • Technique
    anti human, Antibody, Rabbit, anti, antibody to, anti human antibodies, antibodies against human proteins, antibodies for
  • Alternative technique
    antibodies, rabbit-anti