- Catalog numberCSB-PA006237LB01HU_50ug
- Product nameRabbit Anti Human CXADR Antibody-HRP
- Size50ug
- PriceAsk For Price
- Long nameRabbit Antibody against Human CXADR, HRP
- Short nameAnti-CXADR
- Synonym nameCXADR Human Antibody
- HostRabbit, Rabbits
- Species reactivityHuman
- Tested applications recommended dilutionsELISA
- ConjugationHRP
- Antibody isotypeIgG
- UniProt IDP78310
- FormatLiquid, diluted in buffer
- Buffer compositionPreservative: 0.03% Proclin 300, Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
- Purity>95%
- Purification methodProtein G purified
- Antibody categoryPolyclonal Antibodies
- Immunogen typeRecombinant human Coxsackievirus and adenovirus receptor protein (259-365AA)
- Immunogen speciesHuman
- AliasCoxsackievirus and adenovirus receptor,CAR,hCAR,CXADR,CAR,CVB3-binding protein,Coxsackievirus B-adenovirus receptor,HCVADR
- BackgroundComponent of the epithelial apical junction complex that may function as an homophilic cell adhesion molecule and is essential for tight junction integrity. Also involved in transepithelial migration of leukocytes through adhesive interactions with AMICA1/JAML a transmembrane protein of the plasma membrane of leukocytes. The interaction between both receptors also mediates the activation of gamma-delta T-cells, a subpopulation of T-cells residing in epithelia and involved in tissue homeostasis and repair. Upon epithelial CXADR-binding, AMICA1 induces downstream cell signaling events in gamma-delta T-cells through PI3-kinase and MAP kinases. It results in proliferation and production of cytokines and growth factors by T-cells that in turn stimulate epithelial tissues repair.
- ClonalityPolyclonal antibody
- Shipping and storageCXADR Antibody is shipped on ice packs and upon receipt should be stored at -20 or -80 degrees Celsius. We recommend that you prepare the working aliquots in advance so that freez-thaw cycles are avoided. Do not expose the antibodies to drirect bright light, especially the labeled ones as most conjugates are light sensitive.
- Alternative to gene target
- [ "coxsackie virus and adenovirus receptor", "CAR and CAR4/6 and HCAR", "CXADR and IDBG-854 and ENSG00000154639 and 1525", "connexin binding", "nuclei", "Gm1123 and IDBG-192613 and ENSMUSG00000044860 and 382097", "CXADR and IDBG-630474 and ENSBTAG00000004869 and 281733" ]
- Gene targetCXADR -
- Identity:HGNC:2559
- Gene:CXADR
- Long gene name:CXADR Ig-like cell adhesion molecule
- Synonyms gene name:coxsackie virus and adenovirus receptor, CXADR, Ig-like cell adhesion molecule
- Synonyms:CAR,
- Discovery year:1998-03-24
- Entrez gene record:1525
- Pubmed identification:9036860, 9096397, 20813955
- Classification:IgCAM CXADR-related subfamily, V-set domain containing
- VEGA ID:OTTHUMG00000074508
- Gene symbolCXADR
- LabelHRP
- label filter
- HRP
- technique filter
- anti human
- Antibody
- Rabbit
- anti
- Techniqueanti human, Antibody, Rabbit, anti, antibody to, anti human antibodies, antibodies against human proteins, antibodies for
- Alternative techniqueantibodies, rabbit-anti