• Catalog number
    CSB-PA006237LB01HU_100ug
  • Product name
    Rabbit Anti Human CXADR Antibody-HRP
  • Size
    100ug
  • Long name
    Rabbit Antibody against Human CXADR, HRP
  • Short name
    Anti-CXADR
  • Synonym name
    CXADR Human Antibody
  • Host
    Rabbit, Rabbits
  • Species reactivity
    Human
  • Tested applications recommended dilutions
    ELISA
  • Conjugation
    HRP
  • Antibody isotype
    IgG
  • UniProt ID
    P78310
  • Format
    Liquid, diluted in buffer
  • Buffer composition
    Preservative: 0.03% Proclin 300, Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • Purity
    >95%
  • Purification method
    Protein G purified
  • Antibody category
    Polyclonal Antibodies
  • Immunogen type
    Recombinant human Coxsackievirus and adenovirus receptor protein (259-365AA)
  • Immunogen species
    Human
  • Alias
    Coxsackievirus and adenovirus receptor,CAR,hCAR,CXADR,CAR,CVB3-binding protein,Coxsackievirus B-adenovirus receptor,HCVADR
  • Background
    Component of the epithelial apical junction complex that may function as an homophilic cell adhesion molecule and is essential for tight junction integrity. Also involved in transepithelial migration of leukocytes through adhesive interactions with AMICA1/JAML a transmembrane protein of the plasma membrane of leukocytes. The interaction between both receptors also mediates the activation of gamma-delta T-cells, a subpopulation of T-cells residing in epithelia and involved in tissue homeostasis and repair. Upon epithelial CXADR-binding, AMICA1 induces downstream cell signaling events in gamma-delta T-cells through PI3-kinase and MAP kinases. It results in proliferation and production of cytokines and growth factors by T-cells that in turn stimulate epithelial tissues repair.
  • Clonality
    Polyclonal antibody
  • Shipping and storage
    CXADR Antibody is shipped on ice packs and upon receipt should be stored at -20 or -80 degrees Celsius. We recommend that you prepare the working aliquots in advance so that freez-thaw cycles are avoided. Do not expose the antibodies to drirect bright light, especially the labeled ones as most conjugates are light sensitive.
  • Alternative to gene target
    • [ "coxsackie virus and adenovirus receptor", "CAR and CAR4/6 and HCAR", "CXADR and IDBG-854 and ENSG00000154639 and 1525", "connexin binding", "nuclei", "Gm1123 and IDBG-192613 and ENSMUSG00000044860 and 382097", "CXADR and IDBG-630474 and ENSBTAG00000004869 and 281733" ]
  • Gene target
    CXADR -
  • Gene info
  • Gene symbol
    CXADR
  • Label
    HRP
  • label filter
    • HRP
  • technique filter
    • anti human
    • Antibody
    • Rabbit
    • anti
  • Technique
    anti human, Antibody, Rabbit, anti, antibody to, anti human antibodies, antibodies against human proteins, antibodies for
  • Alternative technique
    antibodies, rabbit-anti