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Rabbit Anti Human CD46 Antibody-Non-conjugated

  • Catalog number
    CSB-PA004939EA01HU_50ug
  • Product name
    Rabbit Anti Human CD46 Antibody-Non-conjugated
  • Size
    50ug
  • Long name
    Rabbit Antibody against Human CD46, Non-conjugated
  • Short name
    Anti-CD46
  • Synonym name
    CD46 Human Antibody
  • Host
    Rabbit, Rabbits
  • Species reactivity
    Human
  • Tested applications recommended dilutions
    ELISA,WB,IHC;Recommended dilution:WB:1:200-1000,IHC:1:20-1:200
  • Conjugation
    Non-conjugated
  • Antibody isotype
    IgG
  • UniProt ID
    P15529
  • Format
    Liquid, diluted in buffer
  • Buffer composition
    Preservative: 0.03% Proclin 300, Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • Purity
    >95%
  • Purification method
    Protein G purified
  • Antibody category
    Polyclonal Antibodies
  • Immunogen type
    Recombinant human Membrane cofactor protein (164-325AA)
  • Immunogen species
    Human
  • Alias
    TLX,Trophoblast leukocyte common antigen,CD46,MCP, MIC10
  • Background
    Acts as a cofactor for complement factor I, a serine protease which protects autologous cells against complement-mediated injury by cleaving C3b and C4b deposited on host tissue. May be involved in the fusion of the spermatozoa with the oocyte during fertilization. Also acts as a costimulatory factor for T-cells which induces the differentiation of CD4+ into T-regulatory 1 cells. T-regulatory 1 cells suppress immune responses by secreting interleukin-10, and therefore are thought to prevent autoimmunity. A number of viral and bacterial pathogens seem to exploit this property and directly induce an immunosuppressive phenotype in T-cells by binding to CD46.
  • Clonality
    Polyclonal antibody
  • Shipping and storage
    CD46 Antibody is shipped on ice packs and upon receipt should be stored at -20 or -80 degrees Celsius. We recommend that you prepare the working aliquots in advance so that freez-thaw cycles are avoided. Do not expose the antibodies to drirect bright light, especially the labeled ones as most conjugates are light sensitive.
  • Alternative to gene target
    • [ "CD46 molecule, complement regulatory protein", "AHUS2 and MCP and MIC10 and TLX and TRA2.10", "CD46 and IDBG-106372 and ENSG00000117335 and 4179", "cadherin binding", "Cell surfaces", "Cd46 and IDBG-209330 and ENSMUSG00000016493 and 17221", "BT.68611 and IDBG-638462 and ENSBTAG00000005397 and 280851" ]
  • Gene target
    CD46 Non-conjugated
    • Gene info
    Locus Specific Databases:LRG_155
  • Gene symbol
    CD46
  • technique filter
    • anti human
    • Antibody
    • Rabbit
    • anti
  • Technique
    anti human, Antibody, Rabbit, anti, antibody to, anti human antibodies, antibodies against human proteins, antibodies for, antibody Conjugates
  • Alternative technique
    antibodies, rabbit-anti