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Rabbit Anti Human BVES Antibody-Non-conjugated

  • Catalog number
    CSB-PA002887ESR1HU_100ul
  • Product name
    Rabbit Anti Human BVES Antibody-Non-conjugated
  • Size
    100ul
  • Long name
    Rabbit Antibody against Human BVES, Non-conjugated
  • Short name
    Anti-BVES
  • Synonym name
    BVES Human Antibody
  • Host
    Rabbit, Rabbits
  • Species reactivity
    Human
  • Tested applications recommended dilutions
    ELISA,IF;Recommended dilution:IF:1:50-1:200
  • Conjugation
    Non-conjugated
  • Antibody isotype
    IgG
  • UniProt ID
    Q8NE79
  • Format
    Liquid, diluted in buffer
  • Buffer composition
    PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
  • Purity
    >95%
  • Purification method
    Antigen Affinity Purified Antibodies
  • Antibody category
    Polyclonal Antibodies
  • Immunogen type
    Recombinant human Blood vessel epicardial substance protein (241-360AA)
  • Immunogen species
    Human
  • Alias
    Blood vessel epicardial substanceImported,Popeye domain-containing protein 1,Popeye protein 1,BVES
  • Background
    Cell adhesion molecule involved in the establishment and/or maintenance of cell integrity. Involved in the formation and regulation of the tight junction (TJ) paracellular permeability barrier in epithelial cells (PubMed:16188940). Plays a role in VAMP3-mediated vesicular transport and recycling of different receptor molecules through its interaction with VAMP3. Plays a role in the regulation of cell shape and movement by modulating the Rho-family GTPase activity through its interaction with ARHGEF25/GEFT. Induces primordial adhesive contact and aggregation of epithelial cells in a Ca(2+)-independent manner. Also involved in striated muscle regeneration and repair and in the regulation of cell spreading (By similarity). Important for the maintenance of cardiac function. Plays a regulatory function in heart rate dynamics mediated, at least in part, through cAMP-binding and, probably, by increasing cell surface expression of the potassium channel KCNK2 and enhancing current density (PubMed:26642364). Is also a caveolae-associated protein important for the preservation of caveolae structural and functional integrity as well as for heart protection against ischemia injury.
  • Clonality
    Polyclonal antibody
  • Shipping and storage
    BVES Antibody is shipped on ice packs and upon receipt should be stored at -20 or -80 degrees Celsius. We recommend that you prepare the working aliquots in advance so that freez-thaw cycles are avoided. Do not expose the antibodies to drirect bright light, especially the labeled ones as most conjugates are light sensitive.
  • Short name of the antigen
    Blood vessel epicardial substance
  • Alternative to gene target
    • [ "blood vessel epicardial substance", "HBVES and POP1 and POPDC1", "BVES and IDBG-94774 and ENSG00000112276 and 11149", "cAMP binding", "Cell surfaces", "Bves and IDBG-148896 and ENSMUSG00000071317 and 23828", "BVES and IDBG-631953 and ENSBTAG00000018790 and 539988" ]
  • Gene target
    BVES Non-conjugated
    • Gene info
    Gene info
  • Gene symbol
    BVES, BVES-AS1
  • technique filter
    • anti human
    • Antibody
    • Rabbit
    • anti
  • Technique
    anti human, Antibody, Rabbit, anti, antibody to, anti human antibodies, antibodies against human proteins, antibodies for, antibody Conjugates
  • Alternative technique
    antibodies, rabbit-anti