• Catalog number
    CSB-PA14579A0Rb_50ug
  • Product name
    Rabbit Anti Human A2M Antibody-Non-conjugated
  • Size
    50ug
  • Long name
    Rabbit Antibody against Human A2M, Non-conjugated
  • Short name
    Anti-A2M
  • Synonym name
    A2M Human Antibody
  • Host
    Rabbit, Rabbits
  • Species reactivity
    Human
  • Tested applications recommended dilutions
    ELISA,IHC,IF;Recommended dilution:IHC:1:20-1:200,IF:1:50-1:200
  • Conjugation
    Non-conjugated
  • Antibody isotype
    IgG
  • UniProt ID
    P01023
  • Format
    Liquid, diluted in buffer
  • Buffer composition
    Preservative: 0.03% Proclin 300, Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • Purity
    >95%
  • Purification method
    Protein G purified
  • Antibody category
    Polyclonal Antibodies
  • Immunogen type
    Recombinant human Alpha-2-macroglobulin protein (1216-1467AA)
  • Immunogen species
    Human
  • Alias
    Alpha-2-macroglobulinAlpha-2-M,C3 and PZP-like alpha-2-macroglobulin domain-containing protein 5,A2M,CPAMD5,FWP007
  • Background
    Is able to inhibit all four classes of proteinases by a unique 'trapping' mechanism. This protein has a peptide stretch, called the 'bait region' which contains specific cleavage sites for different proteinases. When a proteinase cleaves the bait region, a conformational change is induced in the protein which traps the proteinase. The entrapped enzyme remains active against low molecular weight substrates (activity against high molecular weight substrates is greatly reduced). Following cleavage in the bait region a thioester bond is hydrolyzed and mediates the covalent binding of the protein to the proteinase.
  • Clonality
    Polyclonal antibody
  • Shipping and storage
    A2M Antibody is shipped on ice packs and upon receipt should be stored at -20 or -80 degrees Celsius. We recommend that you prepare the working aliquots in advance so that freez-thaw cycles are avoided. Do not expose the antibodies to drirect bright light, especially the labeled ones as most conjugates are light sensitive.
  • Short name of the antigen
    Alpha-2-macroglobulin
  • Alternative to gene target
    • [ "alpha-2-macroglobulin", "A2MD and CPAMD5 and FWP007 and S863-7", "A2M and IDBG-17623 and ENSG00000175899 and 2", "calcium-dependent protein binding", "Extracellular", "A2m and IDBG-184734 and ENSMUSG00000030111 and 232345", "A2M and IDBG-639675 and ENSBTAG00000018137 and 513856" ]
  • Gene target
    A2M Non-conjugated
  • Gene info
    Gene info
  • Gene symbol
    A2M-AS1, A2M
  • technique filter
    • anti human
    • Antibody
    • Rabbit
    • anti
  • Technique
    anti human, Antibody, Rabbit, anti, antibody to, anti human antibodies, antibodies against human proteins, antibodies for, antibody Conjugates
  • Alternative technique
    antibodies, rabbit-anti