- Catalog numberCSB-PA14579A0Rb_50ug
- Product nameRabbit Anti Human A2M Antibody-Non-conjugated
- Size50ug
- PriceAsk For Price
- Long nameRabbit Antibody against Human A2M, Non-conjugated
- Short nameAnti-A2M
- Synonym nameA2M Human Antibody
- HostRabbit, Rabbits
- Species reactivityHuman
- Tested applications recommended dilutionsELISA,IHC,IF;Recommended dilution:IHC:1:20-1:200,IF:1:50-1:200
- ConjugationNon-conjugated
- Antibody isotypeIgG
- UniProt IDP01023
- FormatLiquid, diluted in buffer
- Buffer compositionPreservative: 0.03% Proclin 300, Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
- Purity>95%
- Purification methodProtein G purified
- Antibody categoryPolyclonal Antibodies
- Immunogen typeRecombinant human Alpha-2-macroglobulin protein (1216-1467AA)
- Immunogen speciesHuman
- AliasAlpha-2-macroglobulinAlpha-2-M,C3 and PZP-like alpha-2-macroglobulin domain-containing protein 5,A2M,CPAMD5,FWP007
- BackgroundIs able to inhibit all four classes of proteinases by a unique 'trapping' mechanism. This protein has a peptide stretch, called the 'bait region' which contains specific cleavage sites for different proteinases. When a proteinase cleaves the bait region, a conformational change is induced in the protein which traps the proteinase. The entrapped enzyme remains active against low molecular weight substrates (activity against high molecular weight substrates is greatly reduced). Following cleavage in the bait region a thioester bond is hydrolyzed and mediates the covalent binding of the protein to the proteinase.
- ClonalityPolyclonal antibody
- Shipping and storageA2M Antibody is shipped on ice packs and upon receipt should be stored at -20 or -80 degrees Celsius. We recommend that you prepare the working aliquots in advance so that freez-thaw cycles are avoided. Do not expose the antibodies to drirect bright light, especially the labeled ones as most conjugates are light sensitive.
- Short name of the antigenAlpha-2-macroglobulin
- Alternative to gene target
- [ "alpha-2-macroglobulin", "A2MD and CPAMD5 and FWP007 and S863-7", "A2M and IDBG-17623 and ENSG00000175899 and 2", "calcium-dependent protein binding", "Extracellular", "A2m and IDBG-184734 and ENSMUSG00000030111 and 232345", "A2M and IDBG-639675 and ENSBTAG00000018137 and 513856" ]
- Gene targetA2M Non-conjugated
- Identity:HGNC:27057
- Gene:A2M-AS1
- Long gene name:A2M antisense RNA 1
- Synonyms gene name:A2M antisense RNA 1 (non-protein coding), A2M antisense RNA 1
- Discovery year:2012-06-23
- Entrez gene record:144571
- RefSeq identity:NR_026971
- Classification:Antisense RNAs
- VEGA ID:OTTHUMG00000168289
- Identity:HGNC:7
- Gene:A2M
- Long gene name:alpha-2-macroglobulin
- Synonyms:FWP007S863-7CPAMD5
- Discovery year:1986-01-01
- Entrez gene record:2
- Pubmed identification:2408344, 9697696
- RefSeq identity:NM_000014
- Classification:C3 and PZP like, alpha-2-macroglobulin domain containing
- VEGA ID:OTTHUMG00000150267
- Gene symbolA2M-AS1, A2M
- technique filter
- anti human
- Antibody
- Rabbit
- anti
- Techniqueanti human, Antibody, Rabbit, anti, antibody to, anti human antibodies, antibodies against human proteins, antibodies for, antibody Conjugates
- Alternative techniqueantibodies, rabbit-anti
Gene info
Gene info
Locus Specific Databases:LRG_591