- Catalog numberCSB-PA324598LB01HDO_50ug
- Product nameRabbit Anti Hepatitis B virus genotype A2 subtype adw2 P Antibody-HRP
- Size50ug
- PriceAsk For Price
- Long nameRabbit Antibody against Hepatitis B virus genotype A2 subtype adw2 P, HRP
- Short nameAnti-P
- Synonym nameP Hepatitis B virus genotype A2 subtype adw2 Antibody
- HostRabbit, Rabbits
- Species reactivityHepatitis B virus genotype A2 subtype adw2
- Tested applications recommended dilutionsELISA
- ConjugationHRP
- Antibody isotypeIgG
- UniProt IDP17100
- FormatLiquid, diluted in buffer
- Buffer compositionPreservative: 0.03% Proclin 300, Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
- Purity>95%
- Purification methodProtein G purified
- Antibody categoryPolyclonal Antibodies
- Immunogen typeRecombinant Hepatitis B virus genotype A2 subtype adw2 Protein P protein (349-692AA)
- Immunogen speciesHepatitis B virus genotype A2 subtype adw2
- AliasProtein P,P
- BackgroundMultifunctional enzyme that converts the viral RNA genome into dsDNA in viral cytoplasmic capsids. This enzyme displays a DNA polymerase activity that can copy either DNA or RNA templates, and a ribonuclease H (RNase H) activity that cleaves the RNA strand of RNA-DNA heteroduplexes in a partially processive 3'- to 5'-endonucleasic mode. Neo-synthesized pregenomic RNA (pgRNA) are encapsidated together with the P protein, and reverse-transcribed inside the nucleocapsid. Initiation of reverse-transcription occurs first by binding the epsilon loop on the pgRNA genome, and is initiated by protein priming, thereby the 5'-end of (-)DNA is covalently linked to P protein. Partial (+)DNA is synthesized from the (-)DNA template and generates the relaxed circular DNA (RC-DNA) genome. After budding and infection, the RC-DNA migrates in the nucleus, and is converted into a plasmid-like covalently closed circular DNA (cccDNA). The activity of P protein does not seem to be necessary for cccDNA generation, and is presumably released from (+)DNA by host nuclear DNA repair machinery.
- ClonalityPolyclonal antibody
- Shipping and storageP Antibody is shipped on ice packs and upon receipt should be stored at -20 or -80 degrees Celsius. We recommend that you prepare the working aliquots in advance so that freez-thaw cycles are avoided. Do not expose the antibodies to drirect bright light, especially the labeled ones as most conjugates are light sensitive.
- Gene targetHepatitis B virus genotype A2 subtype adw2 P -
- LabelHRP
- label filter
- HRP
- technique filter
- Antibody
- Rabbit
- anti
- TechniqueAntibody, Rabbit, anti, antibody to, antibodies against human proteins, antibodies for
- Alternative techniqueantibodies, rabbit-anti
- Virushepatitis
- virus filter
- hepatitis