- Catalog numberPA1997
- Product nameStanniocalcin 1 Antibody
- Size0,1 mg
- PriceAsk For Price
- Target antigenStanniocalcin 1
- ClonalityPolyclonal antibody
- ClonePolyclonal antibody
- Raised inrabbit
- Type of the antibodyIgG polyclonal antibody
- Product formfreeze-dried
- Reacts with specieshuman
- AnalysesWB
- ImmunogenA synthetic peptide corresponding to a sequence in the middle region of human Stanniocalcin 1(150-167aa QLPNHFSNRYYNRLVRSL), identical to the related rat and mouse sequences.
- Product configurationEach vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.
- PurificationImmunogen affinity purified.
- SolubilizationThe powdered antibody should be dissolved in 0.2 ml of distilled water to achieve final concentration of 500ug/ml
- Storage condtionsKeep the Stanniocalcin 1 Antibodyat minus twenty degrees Celsius for 1 year. The ready-to-use solutions can be stored at four degrees Celsius for a month. Our specialsits recommend to freeze the aliquotes at minus twenty degrees Celsius for long-term application. Multiple procedures of freezing and thawing influence the specifity and reactivity of the antibody in a negative way.
- TipsThe Stanniocalcin 1 Antibody did not cross-reacted with other proteins during the test procedures. This antobdy is intended to be used for research analyses and it is not applicale for in vitro diagnostics.
- BackgroundSTC1(Stanniocalcin 1), also called STC, which is encoded by the STC1 gene. By fluorescence in situ hybridization, Chang et al.(1998) mapped the STC1 gene to chromosome 8p21-p11.2. Wagner et al.(1995) found evidence of STC immunoreactivity in human kidney and serum, suggesting the existence of the hormone in mammals. Zhang et al.(1998) reported a constitutive expression of STC in terminally differentiated neurons. Bell et al.(2001) determined that STC1 was 1 of several transcripts upregulated by umbilical vein endothelial cells during capillary morphogenesis in 3-dimensional collagen matrices.
- Related articles1. Bell, S. E., Mavila, A., Salazar, R., Bayless, K. J., Kanagala, S., Maxwell, S. A., Davis, G. E. Differential gene expression during capillary morphogenesis in 3D collagen matrices: regulated expression of genes involved in basement membrane matrix assembly, cell cycle progression, cellular differentiation and G-protein signaling. J. Cell Sci. 114: 2755-2773, 2001. 2. Chang, A. C.-M., Jeffrey, K. J., Tokutake, Y., Shimamoto, A., Neumann, A. A., Dunham, M. A., Cha, J., Sugawara, M., Furuichi, Y., Reddel, R. R. Human stanniocalcin (STC): genomic structure, chromosomal localization, and the presence of CAG trinucleotide repeats. Genomics 47: 393-398, 1998. 3. Wagner, G. F., Guiraudon, C. C., Milliken, C., Copp, D. H. Immunological and biological evidence for a stanniocalcin-like hormone in human kidney. Proc. Nat. Acad. Sci. 92: 1871-1875, 1995. 4. Zhang, K., Westberg, J. A., Paetau, A., von Boguslawsky, K., Lindsberg, P., Erlander, M., Guo, H., Su, J., Olsen, H. S., Andersson, L. C. High expression of stanniocalcin in differentiated brain neurons. Am. J. Path. 153: 439-445, 1998.
- Gene NameSTC1
- Protein NameStanniocalcin-1
- Gene Full Namestanniocalcin 1
- SynonymsStanniocalcin antibody|Stanniocalcin-1 antibody|STC antibody|STC-1 antibody|Stc1 antibody|STC1_HUMAN antibody
- Uniprot IDP52823
- Gene targetStanniocalcin 1
- Identity:HGNC:11373
- Gene:STC1
- Long gene name:stanniocalcin 1
- Discovery year:1999-01-07
- Entrez gene record:6781
- Pubmed identification:9480753
- VEGA ID:OTTHUMG00000097853
- Gene symbolSTC1
- Short nameStanniocalcin 1 Antibody
- technique filter
- Antibody
- TechniqueAntibody, antibodies against human proteins, antibodies for
- Alternative techniqueantibodies