- Catalog numberPA1485
- Product name12 Lipoxygenase Antibody
- Size0,1 mg
- PriceAsk For Price
- Target antigen12 Lipoxygenase
- ClonalityPolyclonal antibody
- ClonePolyclonal antibody
- Raised inrabbit
- Type of the antibodyIgG polyclonal antibody
- Product formfreeze-dried
- Reacts with specieshuman
- AnalysesWB,IHC-P,ICC
- ImmunogenA synthetic peptide corresponding to a sequence at the C-terminus of human 12 Lipoxygenase(588-604aa RNEQLDWPYEYLKPS).
- Product configurationEach vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.
- PurificationImmunogen affinity purified.
- SolubilizationThe powdered antibody should be dissolved in 0.2 ml of distilled water to achieve final concentration of 500ug/ml
- Storage condtionsKeep the 12 Lipoxygenase Antibodyat minus twenty degrees Celsius for 1 year. The ready-to-use solutions can be stored at four degrees Celsius for a month. Our specialsits recommend to freeze the aliquotes at minus twenty degrees Celsius for long-term application. Multiple procedures of freezing and thawing influence the specifity and reactivity of the antibody in a negative way.
- TipsThe 12 Lipoxygenase Antibody did not cross-reacted with other proteins during the test procedures. This antobdy is intended to be used for research analyses and it is not applicale for in vitro diagnostics.
- BackgroundALOX12, Arachidonate 12-lipoxygenase, is an enzyme that in humans is encoded by the ALOX12 gene. By fluorescence in situ hybridization, the ALOX12 gene is located in band 17p13.1. The gene consists of 14 exons with 13 introns and spans approximately 15 kb of DNAArachidonate 12-lipoxygenase introduces a molecular oxygen into the C-12 position of arachidonic acid to produce 12(S)-hydroperoxy-5,8,10,14-eicosatetraenoic acid. The major pathway of arachidonic acid metabolism in human platelets proceeds via a 12-lipoxygenase enzyme. Expression of the LOG12 gene was detected in human erythroleukemia cells, platelets, and human umbilical vein endothelial cells by reverse transcription-PCR analysis.
- Gene NameALOX12
- Protein NameArachidonate 12-lipoxygenase, 12S-type(12S-LOX/12S-lipoxygenase)
- Gene Full Namearachidonate 12-lipoxygenase
- Synonyms12 LOX antibody|12(S) lipoxygenase antibody|12S LOX antibody|12S-lipoxygenase antibody|12S-LOX antibody|12S-type antibody|ALOX12 antibody|Alox12L antibody|Alox15 antibody|Arachidonate 12 lipoxygenase antibody|Arachidonate 12 lipoxygenase, 12S type antibody|Arachidonate 12 lipoxygenase, leukocyte type antibody|Arachidonate 12-lipoxygenase antibody|EC1.13.11.31 antibody|LOG12 antibody|LOX12_HUMAN antibody|Platelet type lipoxygenase 12 antibody|Platelet-type lipoxygenase 12 antibody
- Uniprot IDP18054
- Gene target12 Lipoxygenase
- Identity:HGNC:429
- Gene:ALOX12
- Long gene name:arachidonate 12-lipoxygenase, 12S type
- Synonyms gene name:arachidonate 12-lipoxygenase
- Synonyms:12S-LOX
- Discovery year:1991-08-07
- Entrez gene record:239
- Pubmed identification:1570320
- Classification:Arachidonate lipoxygenases
- VEGA ID:OTTHUMG00000102088
- Identity:HGNC:432
- Gene:ALOX12P2
- Long gene name:arachidonate 12-lipoxygenase pseudogene 2
- Discovery year:1998-08-26
- Entrez gene record:245
- Pubmed identification:9691181
- VEGA ID:OTTHUMG00000177324
- Gene symbolALOX12, ALOX12B, ALOX12P2
- Short name12 Lipoxygenase Antibody
- technique filter
- Antibody
- TechniqueAntibody, antibodies against human proteins, antibodies for
- Alternative techniqueantibodies