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Human CellExp™ Glypican 3 / GPC3, Cynomolgus Recombinant

  • Catalog number
    P1176-10
  • Product name
    Human CellExp™ Glypican 3 / GPC3, Cynomolgus Recombinant
  • Size
    10 ug
  • Synonyms
    GPC3, OCI5, Glypican-3, GTR2-2, MXR7, DGSX, SDYS, SGB, SGBS, SGBS
  • Alternative names
    GPC3, OCI5, Glypican-3, GTR2-2, MXR7, DGSX, SDYS, SGB, SGBS, SGBS
  • Description
    Cell surface proteoglycan that inhibits the dipeptidyl peptidase activity of DPP4 and involved in modulation of IGF2 interactions with its receptor.
  • Recombinant
    Yes
  • Source
    HEK293 cells
  • Purity by SDS PAGE
    > 85%
  • Assay
    SDS-PAGE
  • Endotoxin Level
    < 1.0 EU per/ug
  • Activity Specifications test method
    Measured by its binding ability in a functional ELISA.
  • Biological activity
    Immobilized Human FGF basic, Tag Free at 0.5 ug/mL (100 ul/well) can bind Cynomolgus Glypican 3, His Tag with a linear range of 1-20 ng/ml.
  • Binding Capacity
    Immobilized Human FGF basic, Tag Free at 0.5 ug/mL (100 ul/well) can bind Cynomolgus Glypican 3, His Tag with a linear range of 1-20 ng/ml.
  • Molecular Weight
    62.7 kDa
  • Storage Temp
    -20°C
  • Shipping
    Gel Pack
  • Shelf Life
    12 months
  • Appearance
    Lyophilized
  • Physical form description
    Lyophilized from 0.22 um filtered solution in PBS pH 7.4. Generally 5-8% Mannitol or Trehalose is added as a protectant before lyophilization.
  • Reconstitution Instructions
    Reconstitute in sterile deionized water to the desired protein concentration.
  • Background Information
    Glypican-3 (GPC3) is also known as Intestinal protein OCI-5, GTR2-2, MXR7, which belongs to the glypican family. Glypican 3 / GPC-3 is highly expressed in lung, liver and kidney. Glypican-3 inhibits the dipeptidyl peptidase activity of DPP4. Glypican-3 may be involved in the suppression/modulation of growth in the predominantly mesodermal tissues and organs, and also may play a role in the modulation of IGF2 interactions with its receptor and thereby modulate its function.
  • Handling
    Centrifuge the vial prior to opening.
  • Usage
    For Research Use Only! Not to be used in humans
  • Datasheet
    Datasheet
  • Alternative to gene target
    • [ "glypican 3", "DGSX and GTR2-2 and MXR7 and OCI-5 and SDYS and SGB and SGBS and SGBS1", "GPC3 and IDBG-86754 and ENSG00000147257 and 2719", "peptidyl-dipeptidase inhibitor activity", "Extracellular", "Gpc3 and IDBG-145213 and ENSMUSG00000055653 and 14734", "GPC3 and IDBG-630953 and ENSBTAG00000020406 and 615239" ]
  • Gene target
    CellExp™ Glypican 3 / GPC3 Cynomolgus
    • Gene info
    Gene info
    Locus Specific Databases:LRG_505
  • Gene symbol
    GPC3-AS1, GPC3
  • Short name
    CellExp™ Glypican 3 / GPC3, Cynomolgus Recombinant
  • technique filter
    • Recombinant
  • Technique
    Recombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. Biovision advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
  • Alternative technique
    rec