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Human CellExp™ CD47, rabbit recombinant

  • Catalog number
    P1077-10
  • Product name
    Human CellExp™ CD47, rabbit recombinant
  • Size
    10 µg
  • Synonyms
    CD47, MER6, IAP, OA3
  • Alternative names
    CD47, MER6, IAP, OA3
  • Description
    Plays a role in cell adhesion modulation of integrins
  • Recombinant
    Yes
  • Source
    HEK 293 cells
  • Purity by SDS PAGE
    >95%
  • Assay
    SDS-PAGE
  • Endotoxin Level
    < 1 EU/ug
  • Molecular Weight
    40.4 kDa
  • Storage Temp
    -20°C
  • Shipping
    Gel pack
  • Shelf Life
    12 months
  • Appearance
    Lyophilized
  • Physical form description
    Lyophilized from 0.22 um filtered solution in PBS, pH7.4. Generally Mannitol or Trehalose is added as a protectant before lyophilization.
  • Reconstitution Instructions
    Reconstitute in sterile deionized water to a concentration of 50 ug/ml.
  • Background Information
    Leukocyte surface antigen CD47 is also known as Antigenic surface determinant protein OA3, Integrin-associated protein (IAP) and Protein MER6. CD47 contains 1 Ig-like V-type (immunoglobulin-like) domain. CD47 is very broadly distributed on normal adult tissues. CD47 has a role in both cell adhesion by acting as an adhesion receptor for THBS1 on platelets, and in the modulation of integrins and plays an important role in memory formation and synaptic plasticity in the hippocampus by similarity. CD47 is the receptor for SIRPA, binding to which prevents maturation of immature dendritic cells and inhibits cytokine production by mature dendritic cells. CD47 Interaction with SIRPG mediates cell-cell adhesion, enhances superantigen-dependent T-cell-mediated proliferation and costimulates T-cell activation.
  • Handling
    Centrifuge the vial prior to opening.
  • Usage
    For Research Use Only! Not to be used in humans
  • Datasheet
    Datasheet
  • Alternative to gene target
    • [ "CD47 molecule", "IAP and MER6 and OA3", "CD47 and IDBG-48744 and ENSG00000196776 and 961", "thrombospondin receptor activity", "Plasma membranes", "Cd47 and IDBG-165137 and ENSMUSG00000055447 and 16423", "CD47 and IDBG-631689 and ENSBTAG00000003585 and 282661" ]
  • Gene target
    CellExp™ CD47
    • Gene info
  • Gene symbol
    CD47
  • Host
    Rabbit, Rabbits
  • Short name
    CellExp™ CD47, rabbit recombinant
  • technique filter
    • Recombinant
    • Rabbit
  • Technique
    Recombinant, Rabbit, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. Biovision advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
  • Alternative technique
    rec, rabbit-anti