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cFMS Receptor Inhibitor IV

  • Catalog number
    B2922-5
  • Product name
    cFMS Receptor Inhibitor IV
  • Size
    5 mg
  • Description
    cFMS Receptor Inhibitor IV is a furan carboxamide compound that is a potent, reversible, and ATP-competitive inhibitor of cFMS (Colony-stimulating Factor-1 Receptor) Tyrosine Kinase. It blocks cFMS autophosphorylation in CSF-1/M-CSF-stimulated HEK-293 cells and in cell-free in vitro kinase assays with IC₅₀ values of 76 nM and 17 nM respectively.
  • CAS Number
    959626-45-0
  • Structure Available
    True
  • Salt Form
    false
  • Molecular Formula
    C₂₂H₂₆N₄O₂
  • Molecular Weight
    378.47
  • Cell Permeable
    True
  • Purity
    97%
  • Solubilities
    5 mg/ml in in DMSO
  • Handling
    Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.
  • Tag Line
    An inhibitor of cFMS/CSF-1R
  • Storage Condition
    -20ºC
  • Shipping Condition
    Gel Pack
  • Shelf Life
    36 months
  • PubChem CID
    28408236
  • PubChem CID Link
    PubChem_CID_Link
  • SMILES
    C1CCN(CC1)C2=CC(=C(C=C2)N3CCCCC3)NC(=O)C4=CC=C(O4)C#N
  • InChi
    InChI=1S/C22H26N4O2/c23-16-18-8-10-21(28-18)22(27)24-19-15-17(25-11-3-1-4-12-25)7-9-20(19)26-13-5-2-6-14-26/h7-10,15H,1-6,11-14H2,(H,24,27)
  • InChi Key
    FQGXFVDABCBEFW-UHFFFAOYSA-N
  • Data Sheet Link
    Data_Sheet_Link
  • MSDS Available
    True
  • Gene target
    cFMS Receptor Inhibitor IV
  • Short name
    cFMS Receptor Inhibitor IV