- Catalog number3706-100
- Product nameCalsenilin Antibody
- Size100 µg
- PriceAsk For Price
- Antibody TargetCalsenilin
- Target Alternative NameKCNIP3 , CSEN , DREAM , KCHIP3 , Calsenilin , KCHIP3 , mgC18289 , KChIP3
- Antibody TypePolyclonal
- IsotypeRabbit IgG
- Species ReactivitiesHuman, mouse, rat
- Immunogen SequenceSynthetic peptide surrounding amino acid 107 of human Calsenilin
- AccessionQ9Y2W7
- Gene Id30818
- AppearanceColorless liquid
- FormLiquid
- Concentration0.2 mg/ml
- Formulation100 µg (0.2 mg/ml) in phosphate buffered saline (PBS), pH 7.2, containing 30% glycerol, 0.5% BSA, 5 mM EDTA and 0.03% proclin
- PurificationAffinity purified
- ApplicationWestern blot
- Application And UsagesWestern blotting (2-6 µg/ml). However, the optimal conditions should be determined individually. The antibody detects ~30 kDa Calsenilin in samples from human, mouse, and rat origins. Jurkat cell lysate can be used as a positive control.
- DescriptionCalsenilin is also known as DREAM and KChlP3. Calsenilin interacts with presenilin-2, a protein involved in Alzheimer’s disease, to reverse presenilin mediated enhancement of calcium signaling. Calsenilin also has pro-apoptotic function, is a substrate for caspase-3, acts as a calcium regulated transcriptional suppressor, and interacts with A-type potassium channels.
- Storage Condition-20 °C
- Shipping Conditiongel pack
- Shelf Life12 months
- UsageFor Research Use Only! Not to be used in humans.
- HandlingThe antibody solution should be gently mixed before use.
- Western Blot VerifiedVerified
- Immunocytochemistry VerifiedNot Verified
- Immunofluorescence VerifiedNot Verified
- Immunoprecipitation VerifiedNot Verified
- FACS VerifiedNot Verified
- ELISA VerifiedNot Verified
- ChIP VerifiedNot Verified
- Flow Cytometry VerifiedNot Verified
- Data Sheet Link
- Gene targetCalsenilin
- Identity:HGNC:15523
- Gene:KCNIP3
- Long gene name:potassium voltage-gated channel interacting protein 3
- Synonyms gene name:calsenilin, presenilin-binding protein, EF hand transcription factor, Kv channel interacting protein 3, calsenilin
- Synonyms:DREAM, KCHIP3
- Discovery year:2001-05-24
- Entrez gene record:30818
- Pubmed identification:9771752, 10078534
- RefSeq identity:NM_013434
- Classification:Potassium voltage-gated channel regulatory subunits, EF-hand domain containing
- VEGA ID:OTTHUMG00000130392
- Gene symbolKCNIP3
- isotype filter
- Rabbit IgG
- Short nameCalsenilin Antibody
- technique filter
- Antibody
- TechniqueAntibody, antibodies against human proteins, antibodies for
- Alternative techniqueantibodies