Calsenilin Antibody

• Catalog number
  3706-100
• Price
  Please ask
• Size
  100 µg

• Antibody Target
  Calsenilin
• Target Alternative Name
  KCNIP3 , CSEN , DREAM , KCHIP3 , Calsenilin , KCHIP3 , mgC18289 , KChIP3
• Antibody Type
  Polyclonal
• Species Reactivities
  Human, mouse, rat
• Immunogen Sequence
  Synthetic peptide surrounding amino acid 107 of human Calsenilin
• Accession
  Q9Y2W7
• Gene Id
  30818
• Appearance
  Colorless liquid
• Form
  Liquid
• Concentration
  0.2 mg/ml
• Formulation
  100 µg (0.2 mg/ml) in phosphate buffered saline (PBS), pH 7.2, containing 30% glycerol, 0.5% BSA, 5 mM EDTA and 0.03% proclin
• Purification
  Affinity purified
• Application
  Western blot
• Application And Usages
  Western blotting (2-6 µg/ml). However, the optimal conditions should be determined individually. The antibody detects ~30 kDa Calsenilin in samples from human, mouse, and rat origins. Jurkat cell lysate can be used as a positive control.
• Description
  Calsenilin is also known as DREAM and KChlP3. Calsenilin interacts with presenilin-2, a protein involved in Alzheimer’s disease, to reverse presenilin mediated enhancement of calcium signaling. Calsenilin also has pro-apoptotic function, is a substrate for caspase-3, acts as a calcium regulated transcriptional suppressor, and interacts with A-type potassium channels.
• Storage Condition
  -20 °C
• Shipping Condition
  gel pack
• Shelf Life
  12 months
• Usage
  For Research Use Only! Not to be used in humans.
• Handling
  The antibody solution should be gently mixed before use.
• Western Blot Verified
  Verified
• Immunocytochemistry Verified
  Not Verified
• Immunofluorescence Verified
  Not Verified
• Immunoprecipitation Verified
  Not Verified
• FACS Verified
  Not Verified
• ELISA Verified
  Not Verified
• ChIP Verified
  Not Verified
• Flow Cytometry Verified
  Not Verified
• Data Sheet Link
• Properties
  If you buy Antibodies supplied by Biovision they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  Calsenilin  
• Gene symbol
  KCNIP3
• Short name
  Calsenilin Antibody
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Isotype
  Rabbit IgG
• Alternative name
  Calsenilin (antibody to-)
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:15523
• Gene
  KCNIP3
• Long gene name
  potassium voltage-gated channel interacting protein 3
• Synonyms gene
  • CSEN
• Synonyms gene name
  • calsenilin, presenilin-binding protein, EF hand transcription factor
  • Kv channel interacting protein 3, calsenilin
• Synonyms
  • DREAM
  • KCHIP3
• Synonyms name
  • calsenilin
  • DRE-antagonist modulator
• GenBank acession
  • AF199599
• Locus
  2q11.1
• Discovery year
  2001-05-24
• Entrez gene record
  30818
• Pubmed identfication
  • 9771752
  • 10078534
• RefSeq identity
  • NM_013434
• Classification
  • Potassium voltage-gated channel regulatory subunits
  • EF-hand domain containing
• VEGA ID
  OTTHUMG00000130392

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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