- Catalog number9639-25
- Product nameBLU9931
- Size25 mg
- PriceAsk For Price
- DescriptionBLU9931 is a potent and irreversible small-molecule inhibitor of FGFR4. It potently inhibits FGFR4 activity (IC₅₀ = 3 nM), but only weakly inhibits FGFR1 (IC₅₀ = 591 nM), FGFR2 (IC₅₀ = 493 nM), and FGFR3 (IC₅₀ = 150 nM) activity.
- CAS Number1538604-68-0
- Structure AvailableYes
- Salt FormNo
- Molecular FormulaC₂₆H₂₂Cl₂N₄O₃
- Molecular Weight509.38
- Cell PermeableYes
- Purity≥98% by HPLC
- SolubilitiesDMSO (>5 mg/ml)
- HandlingProtect from air and light
- Tag LineA potent and irreversible small-molecule inhibitor of FGFR4
- Storage Condition-20°C
- Shipping Conditiongel pack
- Shelf Life36 months
- PubChem CID72710839
- PubChem CID Link
- SMILESCC1=C(C(=CC=C1)NC(=O)C=C)NC2=NC=C3C=C(C=CC3=N2)C4=C(C(=CC(=C4Cl)OC)OC)Cl
- InChiInChI=1S/C26H22Cl2N4O3/c1-5-21(33)30-18-8-6-7-14(2)25(18)32-26-29-13-16-11-15(9-10-17(16)31-26)22-23(27)19(34-3)12-20(35-4)24(22)28/h5-13H,1H2,2-4H3,(H,30,33)(H,29,31,32)
- InChi KeyTXEBNKKOLVBTFK-UHFFFAOYSA-N
- Data Sheet Link
- MSDS AvailableYes
- Gene targetBLU9931
- Short nameBLU9931