- Catalog numberA1383-100
- Product nameAnti-IDH1 Antibody
- Size100 µg
- PriceAsk For Price
- Antibody TargetIDH1
- Target Alternative NameIsocitrate dehydrogenase [NADP] cytoplasmic, R132H, IDH 1 R132H
- Antibody TypePolyclonal
- IsotypeRabbit IgG
- Species ReactivitiesHuman
- Immunogen SequenceHuman recombinant IDH1
- AccessionO75874
- Gene Id3417
- AppearanceColorless liquid
- FormLiquid
- FormulationIn PBS pH 7.2, containing 30% glycerol, 0.5% BSA, 5 mM EDTA and 0.03% proclin
- PurificationAffinity purified
- ApplicationWestern blot
- Positive ControlWestern blot
- Application And UsagesWestern blot: 1-4 µg/ml
- DescriptionMutations of the cytosolic IDH 1 are a common feature in primary human brain cancers. Arginine 132 (R132) of IDH is highly conserved among different isoforms of IDH and is most commonly mutated to Histidine. Mutation of IDH1 R132H leads to accumulation of R(-)-2-hydroxyglutarate (2HG), which correlates with an increased risk for malignant brain tumors.
- Storage Condition-20°C
- Shipping Conditiongel pack
- Shelf Life12 months
- UsageFor Research Use Only! Not to be used in humans.
- HandlingThe antibody solution should be gently mixed before use.
- Western Blot VerifiedVerified
- Immunocytochemistry VerifiedNot Verified
- Immunofluorescence VerifiedNot Verified
- Immunoprecipitation VerifiedNot Verified
- FACS VerifiedNot Verified
- ELISA VerifiedNot Verified
- ChIP VerifiedNot Verified
- Dot Blot VerifiedNot Verified
- Flow Cytometry VerifiedNot Verified
- Data Sheet Link
- Gene targetIDH1
- Identity:HGNC:5382
- Gene:IDH1
- Long gene name:isocitrate dehydrogenase (NADP(+)) 1
- Synonyms gene name:isocitrate dehydrogenase 1 (NADP+), soluble, isocitrate dehydrogenase 1 (NADP+), isocitrate dehydrogenase (NADP(+)) 1, cytosolic
- Discovery year:2001-06-22
- Entrez gene record:3417
- RefSeq identity:NM_005896
- Classification:Isocitrate dehydrogenases
- VEGA ID:OTTHUMG00000132943
- Identity:HGNC:40292
- Gene:IDH1-AS1
- Long gene name:IDH1 antisense RNA 1
- Synonyms gene name:IDH1 antisense RNA 1 (non-protein coding)
- Discovery year:2012-02-24
- Entrez gene record:100507475
- Classification:Antisense RNAs
- VEGA ID:OTTHUMG00000154707
- Gene symbolIDH1, IDH1-AS1
- isotype filter
- Rabbit IgG
- Short nameAnti-IDH1 Antibody
- technique filter
- Antibody
- anti-
- anti
- TechniqueAntibody, anti-, anti, antibody to, antibodies, antibodies against human proteins, antibodies for
- Alternative techniqueantibodies
Gene info
Locus Specific Databases:LRG_610