- Catalog numberA2063-100
- Product nameAnti-CoV-2, MERS & SARS-CoV NP Mouse IgG1 Antibody
- Size100 µg
- PriceAsk For Price
- Antibody TargetSARS-CoV-2, MERS & SARS-CoV NP
- Antibody TypeMonoclonal
- IsotypeIgG1, IgG1
- Species ReactivitiesHuman
- Immunogen SequenceRecombinant Coronavirus Nucleoprotein peptide
- AppearanceColorless liquid
- FormLiquid
- FormulationIn 10 mM PBS, pH 7.2, 0.1% sodium azide
- PurificationAffinity purified using protein A
- ApplicationImmunofluorescence (IF),ELISA
- Application And UsagesELISA, IF
- DescriptionSARS-CoV-2, MERS-CoV and SARS-CoV belong to the family of Coronaviridae and are characterized by large positive-sense RNA genome, that is about 28 - 30 kb in length. One unique feature of SARS-CoV-2, SARS-CoV and MERS-CoV is that two-thirds of the viral genome is translated into two large polyproteins whereas the remaining viral genome is transcribed into sub-genomic RNAs. The two large polyproteins encode multiple non-structural proteins that play an important role in viral replication and transcription. SARS-CoV-2, SARS-CoV and MERS-CoV transcribe multiple sub-genomic RNAs that encode four structural proteins, namely, envelope (E), membrane (M), spike (S), and nucleocapsid (N). Some of the main functions of the nucleocapsid protein are 1) to package the genomic of the virus into long and helical ribonucleoprotein (RNP) complexes, 2) to dimerize and associate with genomic RNA of the virus, as well as interact with other structural proteins of the virus, both of which functions are essential for viral assembly, 3) associate with ER-Golgi complex during virus budding, 4) assist in genomic RNA synthesis, 5) assist RNA chaperone proteins in proper folding of nucleic acids, and 6) play an important role in viral pathogenesis.
- Storage Condition2-8°C (Short term), -20°C (Long term)
- Shipping ConditionGel Pack
- Shelf Life12 months
- UsageFor Research Use Only! Not to be used in humans.
- HandlingThe antibody solution should be gently mixed before use.
- Western Blot VerifiedFalse
- Immunocytochemistry VerifiedFalse
- Immunofluorescence VerifiedTrue
- Immunoprecipitation VerifiedFalse
- FACS VerifiedFalse
- ELISA VerifiedTrue
- ChIP VerifiedFalse
- Dot Blot VerifiedFalse
- Flow Cytometry VerifiedFalse
- Data Sheet Link
- Gene targetCoV-2 MERS SARS-CoV NP IgG1
- Identity:HGNC:10537
- Gene:SARS1
- Long gene name:seryl-tRNA synthetase 1
- Synonyms gene name:seryl-tRNA synthetase
- Synonyms:SERS
- Discovery year:1995-06-09
- Entrez gene record:6301
- Pubmed identification:9431993
- RefSeq identity:NM_006513
- Classification:Aminoacyl tRNA synthetases, Class II
- VEGA ID:OTTHUMG00000011726
- Identity:HGNC:17697
- Gene:SARS2
- Long gene name:seryl-tRNA synthetase 2, mitochondrial
- Synonyms gene name:serine-tRNA ligase, mitochondrial, seryl-tRNA synthetase 2
- Synonyms:FLJ20450, mtSerRSSerRSmtSARSSERSSYS
- Discovery year:2002-10-09
- Entrez gene record:54938
- Pubmed identification:10764807
- RefSeq identity:NM_017827
- Classification:Aminoacyl tRNA synthetases, Class II
- VEGA ID:OTTHUMG00000182691
- Gene symbolSARS1, SARS2
- Hostmouse
- isotype filter
- IgG1
- Short nameAnti-CoV-2, MERS & SARS-CoV NP Mouse IgG1 Antibody
- technique filter
- Antibody
- anti-
- Mouse
- anti
- TechniqueAntibody, anti-, Mouse, anti, antibody to, antibodies, antibodies against human proteins, antibodies for, mouses
- Alternative techniqueantibodies, murine