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Anti-CD117/c-Kit Antibody (C117/370)

  • Catalog number
    A1471-100
  • Product name
    Anti-CD117/c-Kit Antibody (C117/370)
  • Size
    100 µg
  • Antibody Target
    c-Kit/CD117
  • Target Alternative Name
    p145; Steel Factor Receptor; Stem Cell Factor Receptor (SCF-Receptor); Mast Cell Growth Factor Receptor
  • Antibody Type
    Monoclonal
  • Clone
    C117/370
  • Isotype
    Mouse / IgG1, kappa
  • Species Reactivities
    Human
  • Immunogen Sequence
    Recombinant human CD117 protein
  • Accession
    P10721
  • Gene Id
    3815
  • Appearance
    Colorless liquid
  • Form
    Liquid
  • Formulation
    In 10 mM PBS with 0.05% BSA & 0.05% azide
  • Purification
    Protein A/G purification
  • Application
    FC, IF, IHC
  • Positive Control
    IHC: human Gastrointestinal Stromal Tumor
  • Application And Usages
    FC: 0.5-1 ug/1X106 cells, IF: 0.5-1 ug/ml, IHC: 0.5-1 ug/ml
  • Description
    This mAb recognizes a protein of 145kDa, identified as CD117/p145kit. It is found on a wide variety of tumor cells including follicular and papillary carcinoma of thyroid, adenocarcinomas from endometrium, lung, ovary, pancreas, and breast as well as malignant melanoma, endodermal sinus tumor, and small cell carcinoma. However, anti-CD117 has been particularly useful in differentiating gastrointestinal stromal tumors from Kaposis sarcoma, tumors of smooth muscle origin, fibromatosis, and neural tumors of the GI tract. Anti-CD117 is also useful in recognizing myeloblasts in bone marrow biopsy and clot section.
  • Storage Condition
    -20 °C
  • Shipping Condition
    gel pack
  • Shelf Life
    12 months
  • Usage
    For Research Use Only! Not to be used in humans
  • Handling
    The antibody solution should be gently mixed before use
  • Western Blot Verified
    Not Verified
  • Immunocytochemistry Verified
    Verified
  • Immunofluorescence Verified
    Not Verified
  • Immunoprecipitation Verified
    Not Verified
  • FACS Verified
    Not Verified
  • ELISA Verified
    Not Verified
  • ChIP Verified
    Not Verified
  • Dot Blot Verified
    Not Verified
  • Flow Cytometry Verified
    Not Verified
  • Data Sheet Link
    Data_Sheet_Link
  • Alternative to gene target
    • [ "v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog", "C-Kit and CD117 and PBT and SCFR", "KIT and IDBG-18980 and ENSG00000157404 and 3815", "transferase activity", "Extracellular", "Kit and IDBG-172083 and ENSMUSG00000005672 and 16590", "KIT and IDBG-642326 and ENSBTAG00000002699 and 280832" ]
  • Gene target
    CD117/c-Kit C117/370
    • Gene info
    Locus Specific Databases:LRG_307
  • Gene symbol
    KIT
  • isotype filter
    • Mouse IgG1
    • kappa
  • Short name
    Anti-CD117/c-Kit Antibody (C117/370)
  • technique filter
    • Antibody
    • anti-
    • anti
  • Technique
    Antibody, anti-, anti, antibody to, antibodies, antibodies against human proteins, antibodies for
  • Alternative technique
    antibodies, kits