- Catalog numberbs-11963R
- Product nameSORCS2 Antibody
- Size0.1ml
- PriceAsk For Price
- Short nameAnti-SORCS2
- Long nameSORCS2 Primary Polyclonal Antibody
- Also known asSORCS2 PAb
- CategoryPrimary Antibodies
- ConjugationUnconjugated
- HostRabbit (Oryctolagus cuniculus)
- Target AntigenSORCS2
- SpecificityThis is a highly specific antibody against SORCS2.
- Modification sNone
- Modification site sUnmodified antibody
- ClonalityPolyclonal antibody
- Clone numberPolyclonal antibody
- IsotypeImmunoglobulin G (IgG)
- Concentration1ug per 1ul
- SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human SORCS2
- Tested ApplicationsWB, IHC-P, IF(IHC-P)
- Recommended dilutionsWB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)
- Cross reactivityHuman, Mouse, Rat
- Cross reactive species detailsDue to limited amount of testing and knowledge, not every possible cross-reactivity is known.
- Background of the target antigenThere are three SorCS genes that have diverse, partially overlapping functions in the central nervous system. In the developing and mature central nervous system, SorCS1, SorCS2 and SorCS3 genes are expressed in a combinatorial, non-overlapping pattern. SorCS proteins show homology to the mosaic receptor SorLA and the neurotensin receptor sortilin, based on a common VPS10 domain, which is the hallmark of the SorCS receptor family. SorCS2 (sortilin-related VPS10 domain containing receptor 2) is a 1,150 amino acid single-pass type I membrane protein that is highly expressed in brain and kidney. Containing six BNR repeats and a single PKD domain, SorCS2 is encoded by a gene that maps to human chromosome 4, which encodes nearly 6% of the human genome and has the largest gene deserts (regions of the genome with no protein encoding genes) of all of the human chromosomes.
- Purification methodThis antibody was purified via Protein A.
- Storage conditionsKeep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
- Synonym namesKIAA1329; SORCS 2; Sortilin related VPS10 domain containing receptor 2; VPS10 domain receptor protein; VPS10 domain receptor protein SORCS 2; SORC2_HUMAN.
- Gene targetSORCS2
- Identity:HGNC:16698
- Gene:SORCS2
- Long gene name:sortilin related VPS10 domain containing receptor 2
- Synonyms gene name:sortilin-related VPS10 domain containing receptor 2
- Synonyms:KIAA1329
- Discovery year:2004-04-20
- Entrez gene record:57537
- Pubmed identification:11499680
- RefSeq identity:NM_020777
- Classification:MicroRNA protein coding host genes
- VEGA ID:OTTHUMG00000159981
- Gene symbolSORCS2
- isotype filter
- Immunoglobulin G IgG
- technique filter
- Antibody
- TechniqueAntibody, antibodies against human proteins, antibodies for
- Alternative techniqueantibodies