• Catalog number
    bs-9456R
  • Product name
    SIRT5 Antibody
  • Size
    0.1ml
  • Price
    Ask For Price
  • Short name
    Anti-SIRT5
  • Long name
    SIRT5 Primary Polyclonal Antibody
  • Also known as
    SIRT5 PAb
  • Category
    Primary Antibodies
  • Conjugation
    Unconjugated
  • Host
    Rabbit (Oryctolagus cuniculus)
  • Target Antigen
    SIRT5
  • Specificity
    This is a highly specific antibody against SIRT5.
  • Modification s
    None
  • Modification site s
    Unmodified antibody
  • Clonality
    Polyclonal antibody
  • Clone number
    Polyclonal antibody
  • Isotype
    Immunoglobulin G (IgG)
  • Concentration
    1ug per 1ul
  • Immunogen range
    120-170/310
  • Subcellular location
    Mitochondrion
  • Source
    This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human SIRT5
  • Gene ID number
    23408
  • Swiss Prot
    Q9NXA8
  • Tested Applications
    WB, IHC-P, IHC-F, IF(IHC-P), IF(IHC-F)
  • Recommended dilutions
    WB(1:100-1000), IHC-P(1:100-500), IHC-F(1:100-500), IF(IHC-P)(1:50-200), IF(IHC-F)(1:50-200)
  • Cross reactivity
    Human, Mouse, Rat
  • Cross reactive species details
    Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
  • Background of the target antigen
    NAD-dependent lysine demalonylase and desuccinylase that specifically removes malonyl and succinyl groups on target proteins. Activates CPS1 and contributes to the regulation of blood ammonia levels during prolonged fasting: acts by mediating desuccinylation of CPS1, thereby increasing CPS1 activity in response to elevated NAD levels during fasting. Activates SOD1 by mediating its desuccinylation, leading to reduced reactive oxygen species. Has weak NAD-dependent protein deacetylase activity; however this activity may not be physiologically relevant in vivo. Can deacetylate cytochrome c (CYCS) and a number of other proteins in vitro.
  • Purification method
    This antibody was purified via Protein A.
  • Storage conditions
    Keep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
  • Synonym names
    SIR2L5; NAD-dependent protein deacylase sirtuin-5, mitochondrial; Regulatory protein SIR2 homolog 5; SIR2-like protein 5; SIRT5
  • Gene target
    SIRT5
  • Gene info
  • Gene symbol
    SIRT5
  • isotype filter
    • Immunoglobulin G IgG
  • technique filter
    • Antibody
  • Technique
    Antibody, antibodies against human proteins, antibodies for
  • Alternative technique
    antibodies