- Catalog numberbs-9456R
- Product nameSIRT5 Antibody
- Size0.1ml
- PriceAsk For Price
- Short nameAnti-SIRT5
- Long nameSIRT5 Primary Polyclonal Antibody
- Also known asSIRT5 PAb
- CategoryPrimary Antibodies
- ConjugationUnconjugated
- HostRabbit (Oryctolagus cuniculus)
- Target AntigenSIRT5
- SpecificityThis is a highly specific antibody against SIRT5.
- Modification sNone
- Modification site sUnmodified antibody
- ClonalityPolyclonal antibody
- Clone numberPolyclonal antibody
- IsotypeImmunoglobulin G (IgG)
- Concentration1ug per 1ul
- Immunogen range120-170/310
- Subcellular locationMitochondrion
- SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human SIRT5
- Gene ID number23408
- Swiss ProtQ9NXA8
- Tested ApplicationsWB, IHC-P, IHC-F, IF(IHC-P), IF(IHC-F)
- Recommended dilutionsWB(1:100-1000), IHC-P(1:100-500), IHC-F(1:100-500), IF(IHC-P)(1:50-200), IF(IHC-F)(1:50-200)
- Cross reactivityHuman, Mouse, Rat
- Cross reactive species detailsDue to limited amount of testing and knowledge, not every possible cross-reactivity is known.
- Background of the target antigenNAD-dependent lysine demalonylase and desuccinylase that specifically removes malonyl and succinyl groups on target proteins. Activates CPS1 and contributes to the regulation of blood ammonia levels during prolonged fasting: acts by mediating desuccinylation of CPS1, thereby increasing CPS1 activity in response to elevated NAD levels during fasting. Activates SOD1 by mediating its desuccinylation, leading to reduced reactive oxygen species. Has weak NAD-dependent protein deacetylase activity; however this activity may not be physiologically relevant in vivo. Can deacetylate cytochrome c (CYCS) and a number of other proteins in vitro.
- Purification methodThis antibody was purified via Protein A.
- Storage conditionsKeep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
- Synonym namesSIR2L5; NAD-dependent protein deacylase sirtuin-5, mitochondrial; Regulatory protein SIR2 homolog 5; SIR2-like protein 5; SIRT5
- Gene targetSIRT5
- Identity:HGNC:14933
- Gene:SIRT5
- Long gene name:sirtuin 5
- Synonyms gene name:sirtuin (silent mating type information regulation 2, S.cerevisiae, homolog) 5, sirtuin (silent mating type information regulation 2 homolog) 5 (S. cerevisiae)
- Discovery year:2001-03-20
- Entrez gene record:23408
- Pubmed identification:10381378
- Classification:Sirtuins
- VEGA ID:OTTHUMG00000014278
- Gene symbolSIRT5
- isotype filter
- Immunoglobulin G IgG
- technique filter
- Antibody
- TechniqueAntibody, antibodies against human proteins, antibodies for
- Alternative techniqueantibodies