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SFRP1 Antibody

  • Catalog number
    bs-1303R
  • Product name
    SFRP1 Antibody
  • Size
    0.1ml
  • Price
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    SFRP1 Antibody
  • Short name
    Anti-SFRP1
  • Long name
    SFRP1 Primary Polyclonal Antibody
  • Also known as
    SFRP1 PAb
  • Category
    Primary Antibodies
  • Conjugation
    Unconjugated
  • Host
    Rabbit (Oryctolagus cuniculus)
  • Target Antigen
    SFRP1
  • Specificity
    This is a highly specific antibody against SFRP1.
  • Modification s
    None
  • Modification site s
    Unmodified antibody
  • Clonality
    Polyclonal antibody
  • Clone number
    Polyclonal antibody
  • Isotype
    Immunoglobulin G (IgG)
  • Concentration
    1ug per 1ul
  • Immunogen range
    265-310/314
  • Subcellular location
    Secreted
  • Source
    This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human SFRP1
  • Gene ID number
    6422
  • Swiss Prot
    Q8N474
  • Tested Applications
    WB, IHC-P, IF(IHC-P)
  • Recommended dilutions
    WB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)
  • Cross reactivity
    Human, Mouse, Rat
  • Cross reactive species details
    Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
  • Background of the target antigen
    Soluble frizzled-related proteins (sFRPS) function as modulators of Wnt signaling through direct interaction with Wnts. They have a role in regulating cell growth and differentiation in specific cell types. SFRP1 decreases intracellular beta-catenin levels (By similarity). Has antiproliferative effects on vascular cells, in vitro and in vivo, and can induce, in vivo, an angiogenic response. In vascular cell cycle, delays the G1 phase and entry into the S phase (By similarity). In kidney development, inhibits tubule formation and bud growth in metanephroi (By similarity). Inhibits WNT1/WNT4-mediated TCF-dependent transcription.
  • Purification method
    This antibody was purified via Protein A.
  • Storage conditions
    Keep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
  • Synonym names
    FRP; FRP1; FrzA; FRP-1; SARP2; Secreted frizzled-related protein 1; sFRP-1; Secreted apoptosis-related protein 2; SARP-2; SFRP1
  • Alternative to gene target
    • [ "secreted frizzled-related protein 1", "FRP and FRP-1 and FRP1 and FrzA and SARP2", "SFRP1 and IDBG-18868 and ENSG00000104332 and 6422", "Wnt-activated receptor activity", "Extracellular", "Sfrp1 and IDBG-142213 and ENSMUSG00000031548 and 20377", "BT.85254 and IDBG-629640 and ENSBTAG00000027625 and 282068" ]
  • Gene target
    SFRP1
    • Gene info
  • Gene symbol
    SFRP1
  • isotype filter
    • Immunoglobulin G IgG
  • technique filter
    • Antibody
  • Technique
    Antibody, antibodies against human proteins, antibodies for
  • Alternative technique
    antibodies