- Catalog numberbs-1890R
- Product nameSCN2A Antibody
- Size0.1ml
- PriceAsk For Price
- Short nameAnti-SCN2A
- Long nameSCN2A Primary Polyclonal Antibody
- Also known asSCN2A PAb
- CategoryPrimary Antibodies
- ConjugationUnconjugated
- HostRabbit (Oryctolagus cuniculus)
- Target AntigenSCN2A
- SpecificityThis is a highly specific antibody against SCN2A.
- Modification sNone
- Modification site sUnmodified antibody
- ClonalityPolyclonal antibody
- Clone numberPolyclonal antibody
- IsotypeImmunoglobulin G (IgG)
- Concentration1ug per 1ul
- SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human SCN2A
- Gene ID number6326
- Tested ApplicationsWB, IHC-P, IF(IHC-P)
- Recommended dilutionsWB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)
- Cross reactivityHuman, Mouse, Rat
- Cross reactive species detailsDue to limited amount of testing and knowledge, not every possible cross-reactivity is known.
- Background of the target antigenVoltage-gated sodium channels are transmembrane glycoprotein complexes composed of a large alpha subunit with 24 transmembrane domains and one or more regulatory beta subunits. They are responsible for the generation and propagation of action potentials in neurons and muscle. This gene encodes one member of the sodium channel alpha subunit gene family. It is heterogeneously expressed in the brain, and mutations in this gene have been linked to several seizure disorders. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined.
- Purification methodThis antibody was purified via Protein A.
- Storage conditionsKeep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
- Synonym namessodium channel voltage-gated type II alpha; sodium channel, voltage-gated, type II, alpha isoform 2; HBSC II; NAC2; Scn2a; SCN2A_HUMAN; Sodium channel protein type II subunit alpha; Sodium channel protein type 2 subunit alpha; Sodium channel protein type II subunit alpha; Sodium channel protein, brain II subunit alph; Voltage-gated sodium channel subunit alpha Nav1.2; Voltage gated sodium channel subunit alpha Nav1.2; BFIC3; HBA; HBSCI; HBSCII; Nav1.2; NAC2; Nav1.2; SCN2A1; SCN2A2.
- Alternative to gene target
- [ "sodium channel, voltage-gated, type II, alpha subunit", "BFIC3 and BFIS3 and BFNIS and EIEE11 and HBA and HBSCI and HBSCII and Na(v)1.2 and NAC2 and Nav1.2 and SCN2A1 and SCN2A2", "SCN2A and IDBG-74003 and ENSG00000136531 and 6326", "protein binding", "Plasma membranes", "Scn2a1 and IDBG-174901 and ENSMUSG00000075318 and 110876", "BT.99915 and IDBG-641113 and ENSBTAG00000038180 and 539718" ]
- Gene targetSCN2A
- Identity:HGNC:10588
- Gene:SCN2A
- Long gene name:sodium voltage-gated channel alpha subunit 2
- Synonyms gene name:sodium channel, voltage-gated, type II, alpha 2 polypeptide, sodium channel, voltage-gated, type II, alpha 1 polypeptide, sodium channel, voltage-gated, type II, alpha subunit, sodium channel, voltage gated, type II alpha subunit
- Synonyms:Nav1.2, HBSCII, HBSCI,
- Discovery year:1992-08-07
- Entrez gene record:6326
- Pubmed identification:1317301, 16382098
- RefSeq identity:NM_021007
- Classification:Sodium voltage-gated channel alpha subunits
- VEGA ID:OTTHUMG00000044172
- Gene symbolSCN2A
- isotype filter
- Immunoglobulin G IgG
- technique filter
- Antibody
- TechniqueAntibody, antibodies against human proteins, antibodies for
- Alternative techniqueantibodies