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Glycophorin B Antibody

  • Catalog number
    bs-10041R
  • Product name
    Glycophorin B Antibody
  • Size
    0.1ml
  • Short name
    Anti-GYPB
  • Long name
    Glycophorin B Primary Polyclonal Antibody
  • Also known as
    Glycophorin B PAb
  • Category
    Primary Antibodies
  • Conjugation
    Unconjugated
  • Host
    Rabbit (Oryctolagus cuniculus)
  • Target Antigen
    GYPB
  • Specificity
    This is a highly specific antibody against GYPB.
  • Modification s
    None
  • Modification site s
    Unmodified antibody
  • Clonality
    Polyclonal antibody
  • Clone number
    Polyclonal antibody
  • Isotype
    Immunoglobulin G (IgG)
  • Concentration
    1ug per 1ul
  • Immunogen range
    20-59/91
  • Subcellular location
    Extracellular
  • Source
    This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Glycophorin B
  • Gene ID number
    2994
  • Swiss Prot
    P06028
  • Tested Applications
    FCM, IHC-P, IF(IHC-P)
  • Recommended dilutions
    FCM(1:20-100), IHC-P(1:100-500), IF(IHC-P)(1:50-200)
  • Cross reactivity
    Human
  • Cross reactive species details
    Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
  • Background of the target antigen
    Glycophorins A, B and C are sialoglycoproteins of the human erythrocyte membrane, which bear the antigenic determinants for the MN, Ss and Gerbich blood groups, respectively. Glycophorins span the membrane once and present their amino-terminal end to the extracellular surface of the human erythrocyte. The genetic array of expressed glycophorin surface antigens on erythrocytes defines the blood group phenotype of the individual. The human Glycophorin A gene maps to chromosome 4q31.21, contains seven exons which are 97% homologous to Glycophorin B, and encodes a 150 amino acid protein. The human Glycophorin B gene maps to chromosome 4q31.21 and encodes a 91 amino acid protein. The human Glycophorin C gene maps to chromosome 2q14.3 and contains four exons. Glycophorin C transcript can generate two protein isoforms. Isoform 1 includes all 4 exons and encodes the full length 128 amino acid protein. Isoform 2 is missing exon 2 and encodes a 109 amino acid protein, which specifies the Yus subtype of the Gerbich phenotype.
  • Purification method
    This antibody was purified via Protein A.
  • Storage conditions
    Keep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
  • Synonym names
    SS; GPB; MNS; PAS-3; CD235b; GPB.NY; HGpMiX; GpMiIII; HGpMiVI; GYPHe.NY; HGpMiIII; Glycophorin-B; SS-active sialoglycoprotein; Sialoglycoprotein delta; GYPB
  • Gene target
    Glycophorin B
    • Gene info
    Locus Specific Databases:Blood Group Antigen Mutation DatabaseLRG_794
  • Gene symbol
    GYPB
  • isotype filter
    • Immunoglobulin G IgG
  • technique filter
    • Antibody
  • Technique
    Antibody, antibodies against human proteins, antibodies for
  • Alternative technique
    antibodies